Budde W M, Jonas J B
Augenklinik, Friedrich-Alexander-Universität Erlangen-Nürnberg.
Klin Monbl Augenheilkd. 1998 Jan;212(1):37-9. doi: 10.1055/s-2008-1034829.
To evaluate the effect of diabetes mellitus on the optic disc morphology in primary open-angle glaucoma.
Within a group of 364 patients with primary open-angle glaucoma, a subgroup of 52 patients with diabetes mellitus and a second subgroup of 312 patients without diabetes mellitus were compared with each other. Eyes with proliferative diabetic retinopathy had been excluded. Both subgroups were matched for age, gender, and refractive error. The optic disc was morphometrically evaluated using stereo disc photographs.
The two subgroups did not vary significantly (p > 0.10) in mean size of the optic disc, neuroretinal rim and zones Alpha and Beta of the parapapillary chorioretinal atrophy, and frequencies of disc hemorrhages.
Patients with or without diabetes mellitus do not differ significantly in the morphology of the optic disc. One may conclude that diabetes mellitus does not markedly influence planimetric assessed optic disc damage in patients with primary open-angle glaucoma, if eyes with proliferative diabetic retinopathy have been excluded.
评估糖尿病对原发性开角型青光眼视盘形态的影响。
在一组364例原发性开角型青光眼患者中，将52例糖尿病患者亚组与312例非糖尿病患者亚组进行相互比较。增殖性糖尿病视网膜病变的眼睛已被排除。两个亚组在年龄、性别和屈光不正方面进行了匹配。使用立体视盘照片对视盘进行形态学评估。
两个亚组在视盘平均大小、神经视网膜边缘以及视乳头旁脉络膜视网膜萎缩的α区和β区，以及视盘出血频率方面无显著差异（p>0.10）。
有或无糖尿病的患者在视盘形态上无显著差异。可以得出结论，如果排除增殖性糖尿病视网膜病变的眼睛，糖尿病对原发性开角型青光眼患者经平面测量评估的视盘损害没有明显影响。
