Jonas J B, Papastathopoulos K I
Universitäts-Augenklinik Erlangen-Nürnberg.
Ophthalmologe. 1995 Aug;92(4):511-4.
To examine the morphology of the optic disc in eyes with high-pressure open-angle glaucoma.
Using color stereo optic slides, 306 eyes of 183 patients with secondary open-angle glaucoma and 65 eyes of 35 patients with juvenile open-angle glaucoma (group I) were morphometrically examined and compared with 1119 eyes of 585 patients older than 40 years and suffering from with primary open-angle glaucoma (group II).
The eyes of group I as compared to group II showed significantly (P < 0.0001) higher maximal intraocular pressure values and a significantly (P < 0.05) smaller optic disc and parapapillary atrophy. There was a tendency towards steeper and deeper cupping and a lower frequency of optic disc hemorrhages in group I than in group II. The optic disc shape did not vary significantly between the two groups.
Minor parapapillary atrophy suggests high-pressure glaucoma. Barotrauma may be associated with a mostly diffuse damage of the optic nerve. The only slight enlargement of the parapapillary atrophy in the eyes with high-pressure glaucoma indicates that the development of the parapapillary atrophy may at least partially be independent of an elevation of intraocular pressure. The optic disc shape is not useful to identify eyes with high-pressure glaucoma.
研究高压性开角型青光眼患者视盘的形态。
使用彩色立体视盘幻灯片,对183例继发性开角型青光眼患者的306只眼以及35例青少年开角型青光眼患者的65只眼(第一组)进行形态测量检查,并与585例年龄大于40岁的原发性开角型青光眼患者的1119只眼(第二组)进行比较。
与第二组相比,第一组患者的眼内压最高值显著更高(P < 0.0001),视盘和视盘旁萎缩显著更小(P < 0.05)。第一组的视杯倾斜度和深度有增加的趋势,视盘出血频率低于第二组。两组之间视盘形状无显著差异。
轻微的视盘旁萎缩提示高压性青光眼。气压伤可能与视神经的弥漫性损伤有关。高压性青光眼患者视盘旁萎缩仅轻微扩大,表明视盘旁萎缩的发展可能至少部分独立于眼压升高。视盘形状对识别高压性青光眼患者的眼睛无用。