Thines E, Eilbert F, Anke H, Sterner O
Lehrbereich Biotechnologie, University of Kaiserslautern, Germany.
J Antibiot (Tokyo). 1998 Feb;51(2):117-22. doi: 10.7164/antibiotics.51.117.
Glisoprenins C, D, and E, new glisoprenin derivatives, were isolated together with glisoprenin A from submerged cultures of the deuteromycete Gliocladium roseum HA190-95. All glisoprenins inhibited appressorium formation in Magnaporthe grisea on inductive (hydrophobic) surfaces. The compounds exhibited moderate cytotoxic, but no antifungal, antibacterial or phytotoxic activities.
格利索普菌素C、D和E是新的格利索普菌素衍生物,它们与格利索普菌素A一起从半知菌玫瑰粘帚霉HA190 - 95的深层培养物中分离得到。所有的格利索普菌素均能抑制稻瘟病菌在诱导性(疏水)表面形成附着胞。这些化合物表现出中等程度的细胞毒性,但无抗真菌、抗菌或植物毒性活性。