Steinberg D, Kaine G, Gedalia I
Department of Oral Biology, Faculty of Dentistry, Hebrew University-Hadassah, Jerusalem, Israel.
Am J Dent. 1996 Dec;9(6):236-9.
To investigate the antibacterial properties of propolis and honey against oral bacteria in vitro and in vivo.
In vitro study: The antibacterial effects of propolis and honey on oral streptococci were determined using the broth method. Clinical study: The short-term antibacterial effect of propolis solution and honey on salivary total bacteria and Streptococcus mutans was tested in 10 volunteers.
Propolis demonstrated an antibacterial effect both in vitro on isolated oral streptococci and in the clinical study on salivary bacterial counts. Honey induced bacteria growth at low concentrations, while at high concentrations honey had an inhibitory effect on bacterial growth in vitro. Salivary counts of total bacteria and Streptococcus mutans were lower for 1 hour after application of honey. The antibacterial effect of the honey tested may be attributed to its osmolarity effect.
研究蜂胶和蜂蜜在体外和体内对口腔细菌的抗菌特性。
体外研究：采用肉汤法测定蜂胶和蜂蜜对口腔链球菌的抗菌作用。临床研究：在10名志愿者中测试蜂胶溶液和蜂蜜对唾液中总细菌和变形链球菌的短期抗菌作用。
蜂胶在体外对分离出的口腔链球菌以及在临床研究中对唾液细菌计数均显示出抗菌作用。蜂蜜在低浓度时促进细菌生长，而在高浓度时对体外细菌生长具有抑制作用。应用蜂蜜后1小时，唾液中总细菌和变形链球菌的计数较低。所测试蜂蜜的抗菌作用可能归因于其渗透压效应。
