Jain P, Vargas M A, Denehy G E, Boyer D B
Department of Operative Dentistry, University of Iowa, Iowa City 52242, USA.
Am J Dent. 1997 Feb;10(1):21-6.
To evaluate the effect of four proprietary dentin desensitizing agents on dentin tubular occlusion, chemical composition changes on the dentin surface, and the effect of saliva and toothbrushing on these agents.
Fifty dentin discs, obtained from 50 freshly extracted human premolar and molar teeth were used in this study. These were divided into five groups of 10 discs each. Five discs from each group were treated with the desensitizing agents, viewed under the SEM and subjected to energy dispersive X-ray analysis. The other five discs were treated with the desensitizing agents, immersed in artificial saliva, subjected to simulated toothbrushing equivalent to 3 weeks of normal brushing and viewed under the SEM. The agents studied were Sensodyne Dentin Desensitizer, Therma-Trol Desensitizer Gel, Gluma Desensitizer and All-Bond DS.
The Kruskal-Wallis test followed by the Wilcoxon signed-rank test showed that Sensodyne Dentin Desensitizer exhibited the greatest amount of tubular occlusion among the unbrushed samples, followed by Therma-Trol Desensitizer Gel, Gluma Desensitizer and All-Bond DS (P < 0.05) in that order. Toothbrushing increased tubular occlusion in all cases except the Sensodyne Dentin Desensitizer treated samples.
评估四种专利牙本质脱敏剂对牙本质小管封闭的效果、牙本质表面化学成分的变化以及唾液和刷牙对这些脱敏剂的影响。
本研究使用了从50颗新鲜拔除的人类前磨牙和磨牙获取的50个牙本质圆盘。将其分为五组，每组10个圆盘。每组中的五个圆盘用脱敏剂处理，在扫描电子显微镜下观察并进行能量色散X射线分析。另外五个圆盘用脱敏剂处理，浸入人工唾液中，进行相当于正常刷牙3周的模拟刷牙，然后在扫描电子显微镜下观察。所研究的脱敏剂有舒适达牙本质脱敏剂、Therma-Trol脱敏凝胶、Gluma脱敏剂和全粘结DS。
采用Kruskal-Wallis检验，随后进行Wilcoxon符号秩检验，结果显示在未刷牙的样本中，舒适达牙本质脱敏剂表现出最大程度的小管封闭，其次依次为Therma-Trol脱敏凝胶、Gluma脱敏剂和全粘结DS（P < 0.05）。除了用舒适达牙本质脱敏剂处理的样本外，刷牙在所有情况下都增加了小管封闭。
