Grace K L, Revell W J, Brookes M
Department of Orthopedics, UMDS Guy's Hospital, Rayne Institute, London, United Kingdom.
Orthopedics. 1998 Mar;21(3):297-302. doi: 10.3928/0147-7447-19980301-12.
Some clinical studies have claimed significant reductions in the healing time of fresh fractures with the use of pulsed electromagnetic fields (PEMFs). Animal models, however, have produced more equivocal results. This investigation examined the effects of PEMF treatment on an osteochondral defect placed in the patellofemoral groove of the rat. The results indicated that PEMF enhances early vascular reaction and suppresses initial pannus proliferation. Early chondrogenesis and bone formation were consistently stimulated, and the restoration of normal bone trabeculae advanced. Pulsed electromagnetic field treatment therefore may be useful in advancing repair during the early proliferative stage. Later results were variable and suggest that prolonged use may have deleterious effects, enhancing chondrogenesis beyond a point observed in normal repair and thus delaying normal subsurface trabeculation.
一些临床研究称，使用脉冲电磁场（PEMF）可显著缩短新鲜骨折的愈合时间。然而，动物模型的结果却更为模糊。本研究调查了PEMF治疗对大鼠髌股关节沟骨软骨缺损的影响。结果表明，PEMF可增强早期血管反应并抑制初期血管翳增殖。早期软骨形成和骨形成持续受到刺激，正常骨小梁的恢复进程加快。因此，脉冲电磁场治疗可能有助于在早期增殖阶段促进修复。后期结果不一，表明长期使用可能产生有害影响，使软骨形成超过正常修复时的水平，从而延迟正常的软骨下骨小梁形成。
