Pavlov V A
Probl Tuberk. 1998(1):51-4.
Experiments on different groups of guinea pigs inoculated with Mycobacterium tuberculosis (MBT) and intact guinea pigs who received coal refining products and control ones indicated that long exposure to coal-tar resin enhanced mobilization of methionine from the liver with its accumulation in the lung and hematopoietic organs, increased the biosynthesis of arginine in the liver and its accumulation in the lung and hematopoietic organs. MBT drastically enhanced the exchange of the metabolites accumulated in the organs and prevented the formation of adaptive reactions to long-term exposure to polycyclic aromatic hydrocarbons at the level of membranous metabolism.
对不同组接种结核分枝杆菌（MBT）的豚鼠、接受炼焦产品的正常豚鼠以及对照组豚鼠进行的实验表明，长期接触煤焦油树脂会增强蛋氨酸从肝脏的转运，并使其在肺和造血器官中蓄积，增加肝脏中精氨酸的生物合成及其在肺和造血器官中的蓄积。结核分枝杆菌显著增强了器官中积累的代谢物的交换，并在膜代谢水平上阻止了对长期接触多环芳烃形成适应性反应。
