Smith B, Tang Z, Johnson M W, Pourmehdi S, Gazdik M M, Buckett J R, Peckham P H
Cleveland Medical Devices, OH 44106, USA.
IEEE Trans Biomed Eng. 1998 Apr;45(4):463-75. doi: 10.1109/10.664202.
An implantable integrated stimulator and telemetry system has been developed. The system is capable of fulfilling the stimulus and telemetry needs of advanced functional neuromuscular stimulation (FNS) applications requiring multiple channels of stimulation and multiple channels of sensor or biopotential sensing. This system provides a command control structure, an inductive radio frequency link providing power to the implant device as well as two-way transcutaneous communication, an ASIC for decoding the command and for providing functional control within the implant, and modular circuitry providing the application specific implant functions. Biocompatible hermetic packaging, lead systems, and in-line connectors suitable for long-term implantation, provide encapsulation for the circuitry and access to the electrodes and sensors used in the application. The first implant configuration realized from this modular system is targeted for clinical implementation in persons with tetraplegia at the C6 level for restoration of hand function, using wrist position as the command control source. The implant device realized has ten channels of stimulation and telemetry used to control and sense a joint angle transducer implanted in the radio-carpal joint of the wrist. A prototype device has been fabricated and is undergoing testing in an animal.
已开发出一种可植入式集成刺激器和遥测系统。该系统能够满足先进的功能性神经肌肉刺激（FNS）应用的刺激和遥测需求，这些应用需要多通道刺激以及多通道传感器或生物电位传感。该系统提供了一种命令控制结构、一个为植入设备供电以及进行双向经皮通信的感应射频链路、一个用于解码命令并在植入体内提供功能控制的ASIC，以及提供特定应用植入功能的模块化电路。生物相容性密封包装、导联系统和适合长期植入的串联连接器，为电路提供封装，并为应用中使用的电极和传感器提供接入途径。从这个模块化系统实现的首个植入配置目标是用于C6水平四肢瘫痪患者的临床应用，以恢复手部功能，使用手腕位置作为命令控制源。所实现的植入设备有十个刺激和遥测通道，用于控制和感测植入在手腕桡腕关节中的关节角度传感器。已制造出一个原型设备，正在动物身上进行测试。
