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大鼠角膜胆碱酯酶活性的组织化学显示及各种去神经支配对角膜神经的影响。

Histochemical demonstration of cholinesterase activity in the cornea of the rat and the effect of various denervations on the corneal nerves.

作者信息

Tervo T

出版信息

Histochemistry. 1976 May 28;47(2):133-43. doi: 10.1007/BF00492561.

DOI:10.1007/BF00492561
PMID:955974
Abstract

Cholinesterase (ChE) activities of the rat cornea were demonstrated histochemically by using both light and electron microscopes. Acetylcholinesterase (AChE) reaction was localized in the axolemma of the nerves in the corneal stroma. The epithelial cell membranes and the intraepithelial nerve endings also showed AChE reaction. Non-specific cholinesterase (NsChE) activity was observed only in the endothelial cell membranes. Cervical sympathectomy, ciliary ganglionectomy and stereotactic coagulation of the ophthalmic division of the trigeminal nerve were performed in order to study the routes of the AChE-containing nerves to the cornea. The disappearance of AChE-containing nerves was observed only after ophthalmic neurotomy. It is suggested that the AChE-containing nerves are distributed to the rat cornea exclusively via the ophthalamic nerve. They seem to be sensory nerves.

摘要

利用光学显微镜和电子显微镜对大鼠角膜的胆碱酯酶(ChE)活性进行了组织化学证明。乙酰胆碱酯酶(AChE)反应定位于角膜基质中神经的轴膜。上皮细胞膜和上皮内神经末梢也显示出AChE反应。仅在内皮细胞膜中观察到非特异性胆碱酯酶(NsChE)活性。为了研究含AChE神经至角膜的途径,进行了颈交感神经切除术、睫状神经节切除术以及三叉神经眼支的立体定向凝固术。仅在眼神经切断术后观察到含AChE神经的消失。提示含AChE神经仅通过眼神经分布至大鼠角膜。它们似乎是感觉神经。

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本文引用的文献

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