Van Vactor D
Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
Curr Opin Cell Biol. 1998 Apr;10(2):174-81. doi: 10.1016/s0955-0674(98)80139-7.
Protein tyrosine phosphatases (PTPs) constitute a diverse family of intracellular and transmembrane proteins. Expression data and recent genetic analyses indicate that many PTPs play important roles in different aspects of nervous system development. Although PTP mechanisms are still poorly understood, current data suggest considerable complexity in these signaling pathways.
蛋白质酪氨酸磷酸酶（PTPs）构成了一个由细胞内和跨膜蛋白组成的多样化家族。表达数据和近期的基因分析表明，许多PTPs在神经系统发育的不同方面发挥着重要作用。尽管PTP的作用机制仍知之甚少，但目前的数据表明这些信号通路相当复杂。
