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良性前列腺增生患者前列腺基质、血浆雌激素水平与尿雌激素排泄之间的相关性。

Correlation among prostate stroma, plasma estrogen levels, and urinary estrogen excretion in patients with benign prostatic hypertrophy.

作者信息

Seppelt U

出版信息

J Clin Endocrinol Metab. 1978 Dec;47(6):1230-5. doi: 10.1210/jcem-47-6-1230.

DOI:10.1210/jcem-47-6-1230
PMID:95629
Abstract

Plasma testosterone, plasma estradiol, and the total estrogen excretion in the urine were obtained from patients with benign prostatic hypertrophy and correlated to the histological pattern of the resected or enucleated prostates. There was a highly significant increase of prostate stroma in association with higher individual estradiol concentrations and urinary estrogen excretion, while no apparent correlation could be found with testosterone.

摘要

从良性前列腺增生患者中获取血浆睾酮、血浆雌二醇以及尿中总雌激素排泄量，并将其与切除或摘除前列腺的组织学模式相关联。前列腺基质显著增加与个体雌二醇浓度升高及尿雌激素排泄增加相关，而与睾酮未发现明显关联。

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Correlation among prostate stroma, plasma estrogen levels, and urinary estrogen excretion in patients with benign prostatic hypertrophy.良性前列腺增生患者前列腺基质、血浆雌激素水平与尿雌激素排泄之间的相关性。
J Clin Endocrinol Metab. 1978 Dec;47(6):1230-5. doi: 10.1210/jcem-47-6-1230.
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J Steroid Biochem. 1983 Jul;19(1A):155-61.

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Transient neonatal estrogen exposure to estrogen-deficient mice (aromatase knockout) reduces prostate weight and induces inflammation in late life.
短暂性新生期雌激素暴露于雌激素缺乏的小鼠（芳香化酶基因敲除小鼠）会降低成年后的前列腺重量并引发炎症。
Am J Pathol. 2006 Jun;168(6):1869-78. doi: 10.2353/ajpath.2006.050623.
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Studies on the role of sex-hormone-binding globulin (SHBG) in benign prostatic hypertrophy in men. I. Clinical research.性激素结合球蛋白（SHBG）在男性良性前列腺增生中作用的研究。I. 临床研究。
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