Velegraki A, Logotheti M
Department of Microbiology, Medical School, University of Athens, Goudi, Greece.
FEMS Immunol Med Microbiol. 1998 Mar;20(3):239-41. doi: 10.1111/j.1574-695X.1998.tb01132.x.
Developments in medical intervention and the increasing population of patients with immunodeficiencies and transient or long-term immunosuppression have increased the list of yeast species that can cause disease. Candida dubliniensis is a novel species with close genetic relatedness to C. albicans. The two species share many common physiological and biochemical properties thus making their distinction cumbrous. A rapid and inexpensive way to presumptively differentiate between the two species, having previously performed a germ tube test, is the ability of C. dubliniensis to reduce the tetrazolium salt and it is reported for the first time. Microbiological information about new and emerging yeast pathogens, including rapid means for their identification, equips medical microbiologists with the means to identify and physicians to treat effectively infections attributed to unusual yeasts.
医学干预的发展以及免疫缺陷患者和短暂或长期免疫抑制患者数量的增加，使得可导致疾病的酵母种类增多。都柏林念珠菌是一种与白色念珠菌有密切遗传关系的新物种。这两个物种具有许多共同的生理和生化特性，因此区分它们很麻烦。在之前进行芽管试验后，一种快速且廉价的初步区分这两个物种的方法是都柏林念珠菌还原四氮唑盐的能力，这是首次报道。关于新型和新兴酵母病原体的微生物学信息，包括其快速鉴定方法，为医学微生物学家提供了识别手段，也为医生有效治疗由不常见酵母引起的感染提供了方法。
