Swartwood M O, Swartwood J N, Lubar J F, Timmermann D L, Zimmerman A W, Muenchen R A
Department of Psychology, State University of New York, Cortland 13045, USA.
Pediatr Neurol. 1998 Mar;18(3):244-50. doi: 10.1016/s0887-8994(97)00205-1.
The psychophysiologic and behavioral effects of methylphenidate were assessed in boys with attention deficit hyperactivity disorder between the ages of 9 and 11 years. The effects of methylphenidate on the EEG during baseline and cognitive tasks were evaluated using spectral analysis. Both subjective (rating scales) and objective (continuous performance) measures were administered and analyzed in conjunction with the electrophysiologic data. Although methylphenidate induced regional changes in the EEG under certain task-specific conditions, it had no global effects. Behavioral and performance measures improved with methylphenidate.
对9至11岁患有注意力缺陷多动障碍的男孩评估了哌甲酯的心理生理和行为效应。使用频谱分析评估了哌甲酯在基线和认知任务期间对脑电图的影响。主观（评定量表）和客观（连续作业）测量均与电生理数据一起进行管理和分析。尽管哌甲酯在某些特定任务条件下引起脑电图的局部变化，但它没有全局效应。哌甲酯可改善行为和作业测量结果。
