[Lipid peroxidation processes in chronic bronchitis].

AIM

Comparison of the levels of lipid peroxidation (LPO) products in condensate of the exhaled air (CEA) and in the biopsy samples from the inflammation focus.

MATERIALS AND METHODS

Extraction spectrophotometry was used to measure LPO products in CEA and biopsies from 30 males aged 30-60 years suffering from chronic bronchitis and 30 healthy controls of the same age.

RESULTS

There was activation of local accumulation of isopropanol-soluble LPO products in the bronchopulmonary system accompanied by lowered content of lipoperoxides and high antioxidant activity in CEA.

CONCLUSION

Chronic bronchitis is characterized by multidirectional shifts in LPO in the inflammation focus and CEA.