Chervenak F A, Skupski D W, Romero R, Myers M K, Smith-Levitin M, Rosenwaks Z, Thaler H T
Department of Obstetrics and Gynecology, The New York Hospital-Cornell Medical Center, New York 10021, USA.
Am J Obstet Gynecol. 1998 Apr;178(4):678-87. doi: 10.1016/s0002-9378(98)70477-6.
The purpose of the study was to assess the accuracy of fetal biometry in the midtrimester of pregnancy in the assignment of fetal age.
A total of 152 singleton, 67 twin, and 19 triplet gestations resulting from in vitro fertilization with ultrasonographic fetal biometry from 14 to 22 weeks made up the study population. A gestational age prediction equation was derived from singletons with the use of stepwise linear regression. This equation was compared with 38 previously published equations and then applied to the twin and triplet populations.
Head circumference was the best predictor of gestational age (random error [SD] 3.77 days). Addition of abdominal circumference and femur length to head circumference improved the accuracy of the dating equation (random error 3.35 days). Most dating formulas had systematic errors of <1 week. The systematic error was -0.32 day for averaging the singleton-based predictions for twins and -1.26 days for triplets.
Gestational age assessment with the use of fetal biometry from 14 to 22 weeks is accurate for singleton, twin, and triplet gestations.
本研究旨在评估孕中期胎儿生物测量在确定胎儿年龄方面的准确性。
共有152例单胎、67例双胎和19例三胎妊娠,这些妊娠均通过体外受精获得,并对孕14至22周的胎儿进行了超声生物测量,构成了研究人群。利用逐步线性回归从单胎妊娠中推导出生孕周预测方程。将该方程与之前发表的38个方程进行比较,然后应用于双胎和三胎人群。
头围是孕周的最佳预测指标(随机误差[标准差]3.77天)。在头围基础上增加腹围和股骨长度可提高预产期方程的准确性(随机误差3.35天)。大多数预产期公式的系统误差<1周。对双胎基于单胎的预测进行平均时,系统误差为-0.32天,对三胎为-1.26天。
使用孕14至22周的胎儿生物测量评估孕周,对于单胎、双胎和三胎妊娠都是准确的。