Wang Z, Sauve R S
Department of Community Health Sciences, Faculty of Medicine, University of Calgary, AB.
Can J Public Health. 1998 Mar-Apr;89(2):109-14. doi: 10.1007/BF03404400.
To assess growth outcomes of VLBW infants using different growth references and to validate the practice of age adjustment for prematurity in the growth assessment for VLBW infants.
Longitudinal growth data of 514 VLBW infants from 4 to 36 months of adjusted age were analyzed separately based on chronological and adjusted age and by comparison with three growth references.
More infants were labelled as having "subnormal growth" assessed on chronological age than on adjusted age throughout the first three years of life. The proportions of subnormal growth determined using a Canadian and the WHO reference for breastfed infants were similar; they were different from those obtained using the NCHS/WHO reference.
Our findings suggested that the interpretations of growth in VLBW infants vary substantially depending on which reference is used. The age adjustment for prematurity makes substantial difference in identifying subnormal growth in VLBW infants. The adjustment should be carried out throughout the first three years of life.
评估使用不同生长参照标准的极低出生体重儿的生长结局,并验证在极低出生体重儿生长评估中对早产进行年龄校正的做法。
根据实际年龄和校正年龄,分别分析了514例极低出生体重儿从校正年龄4个月至36个月的纵向生长数据,并与三种生长参照标准进行比较。
在生命的头三年中,按实际年龄评估被标记为“生长发育不良”的婴儿比按校正年龄评估的更多。使用加拿大和世界卫生组织母乳喂养婴儿参照标准确定的生长发育不良比例相似;与使用美国国家卫生统计中心/世界卫生组织参照标准得出的比例不同。
我们的研究结果表明,极低出生体重儿生长情况的解读因所使用的参照标准而异。对早产进行年龄校正对识别极低出生体重儿生长发育不良有很大影响。校正应在生命的头三年中进行。