Hellinga H W, Marvin J S
Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA.
Trends Biotechnol. 1998 Apr;16(4):183-9. doi: 10.1016/s0167-7799(98)01174-3.
Biosensors exploit the remarkable specificity of biomolecular recognition to provide analytical tools that can measure the presence of a single molecular species in a complex mixture. A new strategy is emerging in the development of biosensor technologies: molecular-engineering techniques are being used to adapt the properties of proteins to simple, generic detector instrumentation, rather than adapting instruments to the unique requirements of a natural molecule.
生物传感器利用生物分子识别的非凡特异性来提供分析工具,这些工具能够检测复杂混合物中单一分子种类的存在。生物传感器技术的发展正在出现一种新策略:分子工程技术正被用于使蛋白质的特性适应简单的通用检测仪器,而不是使仪器适应天然分子的独特要求。