热成像和甲襞毛细血管镜检查作为雷诺现象患儿循环系统的非侵入性检测方法。

Thermography and nailfold capillaroscopy as noninvasive measures of circulation in children with Raynaud's phenomenon.

作者信息

Jayanetti S, Smith C P, Moore T, Jayson M I, Herrick A L

机构信息

University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford, UK.

出版信息

J Rheumatol. 1998 May;25(5):997-9.

PMID:9598906

Abstract

OBJECTIVE

To determine in a pilot study the feasibility of noninvasive techniques of (a) measurement of rewarming response after a standard cold challenge test (using thermographic imaging) and (b) measurement of nailfold capillary dimensions using video capillaroscopy, in the assessment of children presenting with Raynaud's phenomenon (RP).

METHODS

Ten children with RP and 10 age matched healthy controls were studied. No child had definite evidence of underlying connective tissue disease.

RESULTS

Children with RP had abnormal rewarming curves. The gradient of the rewarming curve was significantly lower in children with RP (median 1.5 vs 5.0 degrees C/min in controls; p = 0.015), and there was a trend for the lag time (the interval between the end of the cold challenge and the onset of rewarming) to be increased in children with RP (median 4.7 vs 0.5 min in controls; p = 0.08). Capillary dimensions were measured in 7 of the children with RP, and were similar to those of healthy controls.

CONCLUSION

Thermography and nailfold capillaroscopy are feasible in children and should be further evaluated.

摘要

目的

在一项初步研究中确定（a）使用热成像技术测量标准冷激发试验后的复温反应以及（b）使用视频毛细血管显微镜测量甲襞毛细血管尺寸等非侵入性技术在评估患有雷诺现象（RP）的儿童中的可行性。

方法

对10名患有RP的儿童和10名年龄匹配的健康对照进行了研究。没有儿童有潜在结缔组织病的确切证据。

结果

患有RP的儿童复温曲线异常。患有RP的儿童复温曲线的斜率显著更低(中位数为1 . 5℃ /分钟，而对照组为5 . 0℃ /分钟；p = 0 . 0 . 结论：热成像和甲襞毛细血管显微镜检查在儿童中是可行的，应进一步评估。 15)，并且患有RP的儿童的延迟时间（冷激发结束与复温开始之间的间隔）有增加的趋势(中位数为4 . 7分钟，而对照组为0 . 5分钟；p = 0 . 08)。在7名患有RP的儿童中测量了毛细血管尺寸，其与健康对照相似。