大鼠2号染色体上11个新型DNA标记与铜蓝蛋白（Cp）基因的遗传连锁图谱构建。

Genetic linkage mapping of 11 novel DNA markers and the ceruloplasmin (Cp) gene on rat chromosome 2.

作者信息

Shepel L A, Fleming R E, Haag J D, Brasic G M, Gheen M E, Simon J S, Gould M N

机构信息

Department of Human Oncology, University of Wisconsin-Madison School of Medicine, 53792, USA.

出版信息

Cytogenet Cell Genet. 1997;79(3-4):176-8. doi: 10.1159/000134714.

DOI:10.1159/000134714

PMID:9605844

Abstract

We have mapped 11 novel, anonymous genetic markers to rat chromosome 2. The rat ceruloplasmin gene (Cp) had been previously mapped to chromosomes 2 and 7q11-->q13 by two different methods. To resolve the assignment and to localize the Cp gene on the rat genetic linkage map, we used linkage analysis to confirm that rat Cp lies on chromosome 2.

摘要

我们已将11个新的、未命名的遗传标记定位到大鼠的2号染色体上。大鼠铜蓝蛋白基因（Cp）先前已通过两种不同方法定位到2号染色体和7号染色体的q11→q13区域。为了明确该基因定位并将Cp基因定位到大鼠遗传连锁图谱上，我们采用连锁分析来确认大鼠Cp基因位于2号染色体上。