岩沙海葵毒素的毒理学评估。
Toxicologic evaluation of yessotoxin.
作者信息
Ogino H, Kumagai M, Yasumoto T
机构信息
Kagome Research Institute, Kagome Co., Ltd., Tochigi, Japan.
出版信息
Nat Toxins. 1997;5(6):255-9. doi: 10.1002/(sici)1522-7189(1997)5:6<255::aid-nt6>3.0.co;2-p.
Abstract
Yessotoxin (YTX), originally found in association with diarrhetic shellfish poisoning (DSP), caused neither intestinal fluid accumulation nor inhibition of protein phosphatase 2A. Orally, YTX was not lethal to mice at 1.0 mg/kg. The toxin showed weak cytotoxic and antifungal activities. Neither hemolytic nor ichthyotoxic effect was observed.
摘要
岩沙海葵毒素（YTX）最初是在与腹泻性贝类中毒（DSP）相关的情况下被发现的，它既不会导致肠液积聚，也不会抑制蛋白磷酸酶2A。经口服，YTX对小鼠的半数致死量为1.0毫克/千克。该毒素表现出微弱的细胞毒性和抗真菌活性。未观察到溶血或鱼毒性作用。
Zotero 插件