Chappey O, Wautier M P, Wautier J L
Laboratoire de biologie vasculaire et cellulaire Hôpital Lariboisière, Paris.
Rev Prat. 1997 Dec 15;47(20):2223-6.
The vascular endothelium is a dynamic interface between blood and tissues, which releases vasoconstrictors or vasodilators regulating the vascular tone. The endothelium modulates the balance between thrombosis and haemorrhage. Activated endothelium may produce tissue factor which triggers the coagulation cascade. In different tissues, the endothelial cells become specialised and may participate to the immune response and inflammation. Various metabolic or immune stimuli may alter endothelial cell functions, induce leukocyte adhesion through expression of specialised molecules and modify the release of fibrinolytic agents, cytokines, and growth factors.
血管内皮是血液与组织之间的动态界面，可释放血管收缩剂或血管扩张剂以调节血管张力。内皮调节血栓形成与出血之间的平衡。活化的内皮可能产生触发凝血级联反应的组织因子。在不同组织中，内皮细胞会特化，并可能参与免疫反应和炎症。各种代谢或免疫刺激可能改变内皮细胞功能，通过特殊分子的表达诱导白细胞黏附，并改变纤溶因子、细胞因子和生长因子的释放。
