Winkler W G, Shaddock J H, Williams L W
Am J Epidemiol. 1976 Sep;104(3):294-8. doi: 10.1093/oxfordjournals.aje.a112302.
The safety of oral rabies vaccine was evaluated in 3 species of rodents, animals which might inadvertently consume field-distributed vaccine baits intended for foxes. The potentials for infection from bait ingestion and transmission through cannibalism were evaluated. Results indicate that ingestion of the vaccine baits used in these experiments will result in infection and disease of some rodents. Of 64 rodents which ate baits, 19 (30%) died of clinical rabies; the diagnosis was confirmed in 11 (17%), and 2 (3%) had demonstrable rabies virus in their salivary glands. Only 3 of 112 (3%) rodents that ate vaccine-infected rodents contracted rabies, and none had demonstrable virus in their salivary glands.
在3种啮齿动物中评估了口服狂犬病疫苗的安全性，这些动物可能会意外食用投放给狐狸的野外疫苗诱饵。评估了因摄入诱饵而感染以及通过同类相食进行传播的可能性。结果表明，食用这些实验中使用的疫苗诱饵会导致一些啮齿动物感染和发病。在64只食用诱饵的啮齿动物中，19只（30%）死于临床狂犬病；11只（17%）的诊断得到证实，2只（3%）的唾液腺中有可检测到的狂犬病病毒。在112只（3%）食用感染疫苗的啮齿动物的啮齿动物中，只有3只感染狂犬病，且它们的唾液腺中均未检测到病毒。
