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通过口服和肌肉注射途径用灭活狂犬病疫苗对赤狐(Vulpes vulpes)进行免疫接种。

Immunization of foxes Vulpes vulpes by the oral and intramuscular routes with inactivated rabies vaccines.

作者信息

Lawson K F, Johnston D H, Patterson J M, Black J G, Rhodes A J, Zalan E

出版信息

Can J Comp Med. 1982 Oct;46(4):382-5.

Abstract

Inactivated rabies vaccines prepared from common vaccine strains of virus were inoculated into foxes by the intramuscular and intestinal route. There were differences among the vaccines in the duration of antibody produced after intramuscular administration. Inactivated vaccines deposited directly into the lumen of the duodenum by means of a fiberscope caused seroconversion in some foxes, especially following a booster dose, but the antibodies produced were for the most part of short duration. The ERA modified live virus vaccine, in contrast, produced a satisfactory and long lasting antibody after intestinal instillation.

摘要

将由普通病毒疫苗株制备的灭活狂犬病疫苗通过肌肉注射和肠道途径接种到狐狸体内。肌肉注射后,不同疫苗产生抗体的持续时间存在差异。通过纤维内窥镜直接将灭活疫苗注入十二指肠腔,在一些狐狸中引起了血清转化,尤其是在加强剂量后,但产生的抗体大多持续时间较短。相比之下,ERA减毒活病毒疫苗在肠道滴注后产生了令人满意且持久的抗体。

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