Nicholson K G, Bauer S P
Arch Virol. 1981;67(1):51-6. doi: 10.1007/BF01314601.
A series of experiments on the safety and efficacy of enteric vaccination was carried out in laboratory rodents using the ERA strain of rabies virus both live and inactivated. In the first and second experiments in white Norway rats, several methods of inoculation were compared for the development of rabies neutralizing antibody. In later experiments, the potential for disease transmission through salivary excretion of ERA strain, or through scavenging, or cannibalism were evaluated. Enteric inoculation of rats with high doses of live ERA virus often failed to give an antibody response yet would occasionally kill adult animals. Rabies antigen was demonstrable in the trigeminal ganglion and tongue of one of these rats, and 14 of 65 (21.5 percent) adult mice died from rabies after eating infants infected with the ERA strain.
使用狂犬病病毒ERA株的活毒株和灭活毒株，在实验啮齿动物身上进行了一系列关于肠道接种疫苗的安全性和有效性的实验。在对白挪威大鼠进行的首次和第二次实验中，比较了几种接种方法以观察狂犬病中和抗体的产生情况。在后续实验中，评估了通过ERA毒株唾液排泄、或通过食腐或同类相食传播疾病的可能性。用高剂量活ERA病毒对大鼠进行肠道接种，往往无法产生抗体反应，但偶尔会导致成年动物死亡。在其中一只大鼠的三叉神经节和舌头中可检测到狂犬病抗原，65只成年小鼠中有14只（21.5%）在食用感染ERA毒株的幼鼠后死于狂犬病。
