Rockwell D, Ruben F L, Winkelstein A, Mendelow H
Am J Med. 1976 Sep;61(3):433-6. doi: 10.1016/0002-9343(76)90383-1.
Progressive multifocal leukoencephalopathy (PML) is a rare disease related to a slow virus infection of the central nervous system; it is usually seen in patients who have impaired immunologic function. The present patient with biopsy-proved PML was found to have no demonstrable defects in either cellular or humoral immunity as assessed by multiple parameters. Thus, it appears that PML may occur in the presence of intact immune responses.
进行性多灶性白质脑病（PML）是一种与中枢神经系统慢病毒感染相关的罕见疾病；通常见于免疫功能受损的患者。经活检证实患有PML的本患者，通过多项参数评估发现其细胞免疫或体液免疫均无明显缺陷。因此，似乎PML可能在免疫反应完整的情况下发生。
