Chisholm I H, Gass J D, Hutton W L
Am J Ophthalmol. 1976 Sep;82(3):343-51. doi: 10.1016/0002-9394(76)90482-7.
Serpiginous and geographic choroiditis, one and the same disease, is characterized by episodic involvement of the pigment epithelium and choroid. Each new lesion passes through an acute phase into an atrophic and scarring one. We observed 20 patients, some with long-term follow-up; some had eventual widespread involvement of both posterior poles. There was no basis for the disease, and treatment did not affect its course. In the patients with long-term disease there was widespread atrophy of the choroid and pigment epithelium and variable amounts of pigment clumping and subretinal fibrous tissue deposition. In nine patients discrete peripheral patches of atrophy were also found. In some eyes the atrophy at the posterior pole had become so confluent that the condition could have been mistaken superficially for a primary choroidal dystrophy. The uninvolved areas appeared to be normal. The electroretinogram and electrooculogram were only affected when extensive disease was present.
匐行性脉络膜炎和地图状脉络膜炎是同一种疾病，其特征为色素上皮和脉络膜的间歇性受累。每个新病灶都要经历急性期，然后进入萎缩和瘢痕形成期。我们观察了20例患者，部分患者进行了长期随访；部分患者最终双眼后极部均广泛受累。该疾病病因不明，治疗不影响其病程。病程较长的患者脉络膜和色素上皮广泛萎缩，伴有不同程度的色素团块和视网膜下纤维组织沉积。9例患者还发现了周边离散的萎缩斑。在一些眼中，后极部的萎缩融合得非常严重，表面上可能会被误诊为原发性脉络膜营养不良。未受累区域看起来正常。只有在广泛病变时，视网膜电图和眼电图才会受到影响。
