Saccomani L, Savoini M, Cirrincione M, Vercellino F, Ravera G
Department of Child Neurology and Psychiatry, University of Genoa, Gaslini Institute, Italy.
J Psychosom Res. 1998 May;44(5):565-71. doi: 10.1016/s0022-3999(97)00210-9.
Eighty-seven children and adolescents with anorexia nervosa, admitted to the Gaslini Department of Child Neurology and Psychiatry between 1976 and 1990, were followed up after a mean of 9.6 years. Outcome measures included the Morgan Russell Outcome Schedule as modified by Jeammet. Outcome was good in 43 (53%) cases, intermediate in 27 (34%) cases, and negative in 11 (14%) cases. No deaths occurred. Based on the Jeammet assessment schedule, the most significant items predicting outcome were insight; sexual, familial, and social relationships; and mental state. Gender of patients and early disease onset did not seem to be predictive measures. Poor outcome was associated with a severe initial clinical picture and length of in-patient treatment. In regard to comorbidity, mood and personality disorders seemed to be negative prognostic indicators, whereas anxiety disorders did not show prognostic value.
1976年至1990年间收治于加斯利尼儿童神经科和精神科的87名神经性厌食症儿童和青少年，平均随访9.6年。结局指标包括经热梅特修改的摩根·拉塞尔结局量表。43例（53%）结局良好，27例（34%）结局中等，11例（14%）结局不良。无死亡病例。根据热梅特评估量表，预测结局的最显著因素是洞察力、性、家庭和社会关系以及精神状态。患者性别和疾病早发似乎不是预测指标。不良结局与严重的初始临床表现和住院治疗时间有关。关于共病，情绪和人格障碍似乎是不良预后指标，而焦虑障碍未显示出预后价值。
