Hecker D, Saul G, Wolf G
Arch Geschwulstforsch. 1976;46(1):34-43.
Comparison was proved from meaning of cell culture and organ culture in therapeutic sensibility tests for cytostatics in ten human ovarial-carcinomas. The sensibility for cytostatics was determined with morphological criteria in cell culture and with the activity-patterns of some enzymes (lactate-dehydrogenase, NADH-diahorase) in organ culture. In these investigations the tumors have shown approximate conformity in the state to cytostatic-sensibility as seen with the two different methods. It seems to be possible, according to these investigations, to use enzyme-histochemical parameters from organ culture for inquiry of cytostatic-sensibility of tumors.
在对10例人类卵巢癌进行的细胞抑制剂治疗敏感性测试中，从细胞培养和器官培养的意义方面进行了比较。在细胞培养中通过形态学标准测定细胞抑制剂的敏感性，在器官培养中通过某些酶（乳酸脱氢酶、NADH-二氢酶）的活性模式测定其敏感性。在这些研究中，用两种不同方法观察到肿瘤在对细胞抑制剂敏感性状态方面显示出大致的一致性。根据这些研究，似乎有可能利用器官培养中的酶组织化学参数来探究肿瘤对细胞抑制剂的敏感性。
