Mendelson G, Aronow W S
Department of Geriatrics and Adult Development, Mount Sinai School of Medicine, New York, New York, USA.
J Am Geriatr Soc. 1998 Jun;46(6):751-2. doi: 10.1111/j.1532-5415.1998.tb03811.x.
To investigate the prevalence of angiotensin-converting enzyme (ACE) inhibitors use in older persons without contraindications to ACE inhibitors and with prior Q-wave anterior myocardial infarction (MI), anterior MI with congestive heart failure (CHF), and with anterior MI and a left ventricular ejection fraction (LVEF) < or = 40% in an academic hospital-based geriatrics practice.
A retrospective analysis of charts from all older patients seen from January 1996 through July 1997 at an academic hospital-based geriatrics practice was performed to investigate the prevalence of ACE inhibitor use in older patients with prior Q-wave anterior MI, anterior MI with CHF, and anterior MI with LVEF < or = 40% without contraindications to ACE inhibitors.
An academic hospital-based primary care geriatrics practice staffed by fellows in a geriatrics training program and full-time faculty geriatricians.
Ninety-six women and 65 men, mean age 82 +/- 8 years (range 65 to 96), were included in the study.
Of 161 patients with Q-wave anterior MI and no contraindications to ACE inhibitors, LVEF was measured in 58 patients (36%), 56 (35%) of whom were receiving ACE inhibitors. Of 45 patients with Q-wave anterior MI and CHF, 30 patients (67%) were receiving ACE inhibitors. Of 15 patients with Q-wave anterior MI and asymptomatic LVEF < or = 40%, four patients (27%) were receiving ACE inhibitors.
There is a marked underutilization of use of ACE inhibitors in treating older patients with Q-wave anterior MI in an academic hospital-based geriatrics practice.
在一家以学术医院为基础的老年医学诊所中,调查无血管紧张素转换酶(ACE)抑制剂使用禁忌且曾患Q波前壁心肌梗死(MI)、前壁MI合并充血性心力衰竭(CHF)以及前壁MI且左心室射血分数(LVEF)≤40%的老年人中ACE抑制剂的使用情况。
对1996年1月至1997年7月在一家以学术医院为基础的老年医学诊所就诊的所有老年患者的病历进行回顾性分析,以调查在无ACE抑制剂使用禁忌的情况下,曾患Q波前壁MI、前壁MI合并CHF以及前壁MI且LVEF≤40%的老年患者中ACE抑制剂的使用情况。
一家以学术医院为基础的初级保健老年医学诊所,由老年医学培训项目的研究员和全职老年医学教员组成。
96名女性和65名男性纳入研究,平均年龄82±8岁(范围65至96岁)。
在161例有Q波前壁MI且无ACE抑制剂使用禁忌的患者中,58例(36%)测量了LVEF,其中56例(35%)正在接受ACE抑制剂治疗。在45例有Q波前壁MI且合并CHF的患者中,30例(67%)正在接受ACE抑制剂治疗。在15例有Q波前壁MI且无症状LVEF≤40%的患者中,4例(27%)正在接受ACE抑制剂治疗。
在一家以学术医院为基础的老年医学诊所中,ACE抑制剂在治疗有Q波前壁MI的老年患者中的使用明显不足。