Reigart J R, Graber C D
Bull Environ Contam Toxicol. 1976 Jul;16(1):112-7. doi: 10.1007/BF01753115.
Twelve lead-exposed children, with evidence of metabolic impairment, and seven non-lead exposed children were examined for evidence of impairment of their immunological response. There were no differences between the control group and the lead exposed group with reference to complement levels, immunoglobulins, or anamnestic response to the tetanus toxoid antigen. It remains to be demonstrated whether or not there is deficient response to primary immunization, whether other antigens are more affected by lead, or whether impairment of humoral immune response requires a more serious degree of lead intoxication.
对12名有代谢损伤证据的铅暴露儿童和7名无铅暴露儿童进行了免疫反应损伤证据的检查。在补体水平、免疫球蛋白或对破伤风类毒素抗原的回忆反应方面，对照组和铅暴露组之间没有差异。对于初次免疫是否存在反应不足、其他抗原是否更易受铅影响，或者体液免疫反应损伤是否需要更严重程度的铅中毒，仍有待证实。
