慢性肝病患者血浆和血清补体的差异
Differences between plasma and serum complement in patients with chronic liver disease.
作者信息
Inai S, Kitamura H, Fujita T, Kojima J, Nagaki K
出版信息
Clin Exp Immunol. 1976 Sep;25(3):403-9.
Abstract
Of sixty patients with chronic liver disease, eight with cirrhosis or chronic hepatitis had very low serum CH50 but normal plasma CH50. The complement component profiles of these sera revealed markedly decreased C4 and C2 activities and normal C3T (C3-C9) activities. From these results, it is suggested that the early acting complement components had been non-specifically activated during blood coagulation in these patients. No difference between plasma and serum CH50 was found in patients with hepatitis B(s) antigen.
摘要
在60例慢性肝病患者中，8例肝硬化或慢性肝炎患者血清CH50极低，但血浆CH50正常。这些血清的补体成分谱显示C4和C2活性明显降低，C3T（C3 - C9）活性正常。从这些结果推测，在这些患者的血液凝固过程中，早期起作用的补体成分被非特异性激活。乙肝表面抗原阳性患者的血浆和血清CH50未发现差异。
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