枯草芽孢杆菌四环素敏感菌株的tetA(L)突变体，其多核苷酸磷酸化酶基因已缺失。
tetA(L) mutants of a tetracycline-sensitive strain of Bacillus subtilis with the polynucleotide phosphorylase gene deleted.
作者信息
Bechhofer D H, Stasinopoulos S J
机构信息
Department of Biochemistry, Mount Sinai School of Medicine, City University of New York, New York 10029, USA.
出版信息
J Bacteriol. 1998 Jul;180(13):3470-3. doi: 10.1128/JB.180.13.3470-3473.1998.
Abstract
A Bacillus subtilis strain with the polynucleotide phosphorylase gene deleted was sensitive for growth in the presence of tetracycline. This strain was used to select for tetracycline-resistant mutants. A point mutation in the tetA(L) promoter and a spontaneously occurring tetA(L) gene copy number mutant were characterized.
摘要
一株缺失多核苷酸磷酸化酶基因的枯草芽孢杆菌菌株在四环素存在的情况下生长敏感。该菌株用于筛选四环素抗性突变体。对tetA(L)启动子中的一个点突变和一个自发产生的tetA(L)基因拷贝数突变体进行了表征。
相似文献
1
tetA(L) mutants of a tetracycline-sensitive strain of Bacillus subtilis with the polynucleotide phosphorylase gene deleted.枯草芽孢杆菌四环素敏感菌株的tetA(L)突变体，其多核苷酸磷酸化酶基因已缺失。
J Bacteriol. 1998 Jul;180(13):3470-3. doi: 10.1128/JB.180.13.3470-3473.1998.
2
Properties of a Bacillus subtilis polynucleotide phosphorylase deletion strain.枯草芽孢杆菌多核苷酸磷酸化酶缺失菌株的特性
J Bacteriol. 1996 Apr;178(8):2375-82. doi: 10.1128/jb.178.8.2375-2382.1996.
3
Bacillus subtilis tetA(L) gene expression: evidence for regulation by translational reinitiation.枯草芽孢杆菌tetA(L)基因表达：通过翻译重新起始进行调控的证据。
Mol Microbiol. 1998 Dec;30(5):923-32. doi: 10.1046/j.1365-2958.1998.01119.x.
4
Two types of Bacillus subtilis tetA(L) deletion strains reveal the physiological importance of TetA(L) in K(+) acquisition as well as in Na(+), alkali, and tetracycline resistance.两种枯草芽孢杆菌tetA(L)缺失菌株揭示了TetA(L)在钾离子摄取以及钠、碱和四环素抗性方面的生理重要性。
J Bacteriol. 2000 Apr;182(8):2088-95. doi: 10.1128/JB.182.8.2088-2095.2000.
5
Chromosomal tetA(L) gene of Bacillus subtilis: regulation of expression and physiology of a tetA(L) deletion strain.枯草芽孢杆菌的染色体tetA(L)基因：tetA(L)缺失菌株的表达调控与生理学研究
J Bacteriol. 1996 May;178(10):2853-60. doi: 10.1128/jb.178.10.2853-2860.1996.
6
An IS257-derived hybrid promoter directs transcription of a tetA(K) tetracycline resistance gene in the Staphylococcus aureus chromosomal mec region.一个源自IS257的杂交启动子指导金黄色葡萄球菌染色体mec区域中tetA(K)四环素抗性基因的转录。
J Bacteriol. 2000 Jun;182(12):3345-52. doi: 10.1128/JB.182.12.3345-3352.2000.
7
Second-site suppressor mutations for the Asp-66-->Cys mutant of the transposon Tn10-encoded metal-tetracycline/H+ antiporter of Escherichia coli.大肠杆菌转座子Tn10编码的金属四环素/H⁺反向转运蛋白Asp-66→Cys突变体的第二位点抑制突变
Biochemistry. 1995 Sep 19;34(37):11800-6. doi: 10.1021/bi00037a018.
8
Global analysis of mRNA decay intermediates in Bacillus subtilis wild-type and polynucleotide phosphorylase-deletion strains.枯草芽孢杆菌野生型和多核苷酸磷酸化酶缺失菌株中mRNA衰变中间体的全局分析。
Mol Microbiol. 2014 Oct;94(1):41-55. doi: 10.1111/mmi.12748. Epub 2014 Aug 21.
9
The yvaJ gene of Bacillus subtilis encodes a 3'-to-5' exoribonuclease and is not essential in a strain lacking polynucleotide phosphorylase.枯草芽孢杆菌的yvaJ基因编码一种3'至5'外切核糖核酸酶，在缺乏多核苷酸磷酸化酶的菌株中并非必需。
J Bacteriol. 2000 May;182(9):2639-42. doi: 10.1128/JB.182.9.2639-2642.2000.
10
Distribution and molecular characterization of tetracycline resistance in Laribacter hongkongensis.香港海鸥菌中四环素抗性的分布及分子特征
J Antimicrob Chemother. 2008 Mar;61(3):488-97. doi: 10.1093/jac/dkm539. Epub 2008 Jan 28.
引用本文的文献
1
Directing microbial co-culture composition using cybernetic control.利用控制论控制指导微生物共培养组成
Cell Rep Methods. 2025 Mar 24;5(3):101009. doi: 10.1016/j.crmeth.2025.101009.
2
Multiplexed in-situ mutagenesis driven by a dCas12a-based dual-function base editor.基于 dCas12a 的双功能碱基编辑器的多路复用原位诱变。
Nucleic Acids Res. 2024 May 8;52(8):4739-4755. doi: 10.1093/nar/gkae228.
3
Analysis of mRNA Decay Intermediates in Bacillus subtilis 3' Exoribonuclease and RNA Helicase Mutant Strains.枯草芽孢杆菌3'外切核糖核酸酶和RNA解旋酶突变菌株中mRNA衰变中间体的分析
mBio. 2022 Apr 26;13(2):e0040022. doi: 10.1128/mbio.00400-22. Epub 2022 Mar 21.
4
Bacterial ribonucleases and their roles in RNA metabolism.细菌核糖核酸酶及其在 RNA 代谢中的作用。
Crit Rev Biochem Mol Biol. 2019 Jun;54(3):242-300. doi: 10.1080/10409238.2019.1651816.
5
Draft genome comparison of representatives of the three dominant genotype groups of dairy Bacillus licheniformis strains.三种主要基因型的奶牛地衣芽孢杆菌菌株代表的基因组草图比较
Appl Environ Microbiol. 2014 Jun;80(11):3453-62. doi: 10.1128/AEM.00065-14. Epub 2014 Mar 21.
6
Polynucleotide phosphorylase has an impact on cell biology of Campylobacter jejuni.多核苷酸磷酸化酶对空肠弯曲菌的细胞生物学有影响。
Front Cell Infect Microbiol. 2012 Mar 14;2:30. doi: 10.3389/fcimb.2012.00030. eCollection 2012.
7
5' End-independent RNase J1 endonuclease cleavage of Bacillus subtilis model RNA.枯草芽孢杆菌模型 RNA 的 5' 端非依赖 RNase J1 内切酶切割。
J Biol Chem. 2011 Oct 7;286(40):34932-40. doi: 10.1074/jbc.M111.287409. Epub 2011 Aug 23.
8
Tetracycline resistance-encoding plasmid from Bacillus sp. strain #24, isolated from the marine sponge Haliclona simulans.来自海洋海绵 Haliclona simulans 的芽孢杆菌#24 菌株的携带四环素抗性的质粒。
Appl Environ Microbiol. 2011 Jan;77(1):327-9. doi: 10.1128/AEM.01239-10. Epub 2010 Nov 5.
9
Adaptive gene expression in Bacillus subtilis strains deleted for tetL.缺失tetL基因的枯草芽孢杆菌菌株中的适应性基因表达
J Bacteriol. 2006 Oct;188(20):7090-100. doi: 10.1128/JB.00885-06.
10
Tetracycline induces stabilization of mRNA in Bacillus subtilis.四环素可诱导枯草芽孢杆菌中mRNA的稳定性。
J Bacteriol. 2002 Feb;184(4):889-94. doi: 10.1128/jb.184.4.889-894.2002.
本文引用的文献
1
Polynucleotide phosphorylase is necessary for competence development in Bacillus subtilis.多核苷酸磷酸化酶对于枯草芽孢杆菌感受态的形成是必需的。
Mol Microbiol. 1996 Jan;19(2):343-56. doi: 10.1046/j.1365-2958.1996.380907.x.
2
In vitro processing activity of Bacillus subtilis polynucleotide phosphorylase.枯草芽孢杆菌多核苷酸磷酸化酶的体外加工活性。
Mol Microbiol. 1996 Jan;19(2):329-42. doi: 10.1046/j.1365-2958.1996.378906.x.
3
Properties of a Bacillus subtilis polynucleotide phosphorylase deletion strain.枯草芽孢杆菌多核苷酸磷酸化酶缺失菌株的特性
J Bacteriol. 1996 Apr;178(8):2375-82. doi: 10.1128/jb.178.8.2375-2382.1996.
4
Chromosomal tetA(L) gene of Bacillus subtilis: regulation of expression and physiology of a tetA(L) deletion strain.枯草芽孢杆菌的染色体tetA(L)基因：tetA(L)缺失菌株的表达调控与生理学研究
J Bacteriol. 1996 May;178(10):2853-60. doi: 10.1128/jb.178.10.2853-2860.1996.
5
Bacillus subtilis strains carry highly homologous direct repeat sequences on their chromosomes.枯草芽孢杆菌菌株在其染色体上携带高度同源的直接重复序列。
Biosci Biotechnol Biochem. 1995 Nov;59(11):2149-50. doi: 10.1271/bbb.59.2149.
6
7
Tetracycline/H+ antiport and Na+/H+ antiport catalyzed by the Bacillus subtilis TetA(L) transporter expressed in Escherichia coli.由在大肠杆菌中表达的枯草芽孢杆菌TetA(L)转运蛋白催化的四环素/H⁺反向转运和Na⁺/H⁺反向转运
J Bacteriol. 1995 Aug;177(15):4557-61. doi: 10.1128/jb.177.15.4557-4561.1995.
8
Compilation and analysis of Bacillus subtilis sigma A-dependent promoter sequences: evidence for extended contact between RNA polymerase and upstream promoter DNA.枯草芽孢杆菌σA依赖型启动子序列的汇编与分析：RNA聚合酶与上游启动子DNA之间存在广泛接触的证据
Nucleic Acids Res. 1995 Jul 11;23(13):2351-60. doi: 10.1093/nar/23.13.2351.
9
Mutations of the Escherichia coli lacUV5 promoter resulting in increased expression in Bacillus subtilis.大肠杆菌lacUV5启动子的突变导致其在枯草芽孢杆菌中的表达增加。
Mol Gen Genet. 1987 Oct;209(3):467-74. doi: 10.1007/BF00331151.
10
Amplification of the amyE-tmrB region on the chromosome in tunicamycin-resistant cells of Bacillus subtilis.枯草芽孢杆菌衣霉素抗性细胞中染色体上amyE-tmrB区域的扩增。
Mol Gen Genet. 1986 Jul;204(1):36-43. doi: 10.1007/BF00330184.
Zotero 插件