• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

溃疡性结肠炎中癌胚抗原（CEA）的组织学表现

Tissue demonstration of carcinoembryonic antigen (CEA) in ulcerative colitis.

作者信息

Isaacson P

出版信息

Gut. 1976 Jul;17(7):561-7. doi: 10.1136/gut.17.7.561.

DOI:10.1136/gut.17.7.561
PMID:964689
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1411163/
Abstract

An immunoperoxidase technique was used to demonstrate carcinoembryonic antigen (CEA) in sections of proctocolectomy specimens from nine cases of ulcerative colitis in some of which carcinoma and premalignant change had developed. Carcinoma and premalignant change stained positively for CEA in contrast with benign mucosa, whether or not inflammatory dysplasia was present.

摘要

采用免疫过氧化物酶技术，对9例溃疡性结肠炎患者的直肠结肠切除标本切片进行癌胚抗原（CEA）检测，其中部分病例已发生癌变和癌前病变。无论是否存在炎症发育异常，癌组织和癌前病变组织CEA染色呈阳性，而良性黏膜呈阴性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/fe62579bb40b/gut00488-0084-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/3f21e3e8915c/gut00488-0081-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/9afeb3949ba4/gut00488-0081-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/0ca1eee49288/gut00488-0082-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/398584b848ec/gut00488-0082-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/c760bd43bb71/gut00488-0080-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/e868ae5d7b39/gut00488-0083-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/fe62579bb40b/gut00488-0084-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/3f21e3e8915c/gut00488-0081-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/9afeb3949ba4/gut00488-0081-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/0ca1eee49288/gut00488-0082-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/398584b848ec/gut00488-0082-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/c760bd43bb71/gut00488-0080-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/e868ae5d7b39/gut00488-0083-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0530/1411163/fe62579bb40b/gut00488-0084-a.jpg

相似文献

1
Tissue demonstration of carcinoembryonic antigen (CEA) in ulcerative colitis.溃疡性结肠炎中癌胚抗原（CEA）的组织学表现
Gut. 1976 Jul;17(7):561-7. doi: 10.1136/gut.17.7.561.
2
[Tissue demonstration of CEA in colorectal lesions (author's transl)].
Nihon Shokakibyo Gakkai Zasshi. 1980 Oct;77(10):1562-5.
3
Tissue carcinoembryonic antigen, dysplasia, and disease duration in colonic inflammatory bowel disease.结肠炎性肠病中的组织癌胚抗原、发育异常及病程
Am J Gastroenterol. 1982 Apr;77(4):212-5.
4
Immunohistochemical demonstration of carcinoembryonic antigen in normal, transitional and inflamed colonic mucosa.癌胚抗原在正常、移行和炎症性结肠黏膜中的免疫组织化学显示
Oncodev Biol Med. 1981;2(5):331-43.
5
Immunoperoxidase staining for CEA in ulcerative colitis.溃疡性结肠炎中癌胚抗原的免疫过氧化物酶染色
J Clin Gastroenterol. 1983 Oct;5(5):453-9. doi: 10.1097/00004836-198310000-00014.
6
Estimation of carcinoembryonic antigen in ulcerative colitis with special reference to malignant change.溃疡性结肠炎中癌胚抗原的测定及其与恶变的关系
Gut. 1975 Apr;16(4):255-60. doi: 10.1136/gut.16.4.255.
7
Immunohistochemical evaluation of carcinoembryonic antigen, secretory component, and epithelial IgA in ulcerative colitis with dysplasia.伴有发育异常的溃疡性结肠炎中癌胚抗原、分泌成分和上皮性IgA的免疫组织化学评估
Gut. 1982 Feb;23(2):123-33. doi: 10.1136/gut.23.2.123.
8
The significance of elevation of serum carcinoembryonic antigen (CEA) levels in inflammatory diseases of the intestine.血清癌胚抗原（CEA）水平升高在肠道炎性疾病中的意义。
Scand J Gastroenterol. 1974;9(7):651-6.
9
Expression of carcinoembryonic antigen in ulcerative colitis, tubular adenomas and hyperplastic polyps: correlations with the degree of dysplasia.
Anticancer Res. 1991 Sep-Oct;11(5):1671-5.
10
Gastrointestinal carcinoma-associated antigen detected by a monoclonal antibody in dysplasia and adenocarcinoma associated with chronic ulcerative colitis.
Int J Cancer. 1985 Aug 15;36(2):131-6. doi: 10.1002/ijc.2910360202.

引用本文的文献

1
The increase of carcinoembryonic antigen (CEA), high-sensitivity C-reactive protein, and neutrophil/lymphocyte ratio in Parkinson's disease.帕金森病中癌胚抗原（CEA）、高敏C反应蛋白及中性粒细胞/淋巴细胞比值的升高
Neurol Sci. 2015 Mar;36(3):423-8. doi: 10.1007/s10072-014-1976-1. Epub 2014 Oct 7.
2
Immunohistochemical evaluation of carcinoembryonic antigen, secretory component, and epithelial IgA in ulcerative colitis with dysplasia.伴有发育异常的溃疡性结肠炎中癌胚抗原、分泌成分和上皮性IgA的免疫组织化学评估
Gut. 1982 Feb;23(2):123-33. doi: 10.1136/gut.23.2.123.
3
Immunohistochemistry of epithelial cell markers in normal and pathological colon mucosa. Comparison of results based on routine formalin- and cold ethanol-fixation methods.

本文引用的文献

1
Rectal biopsy as an aid to cancer control in ulcerative colitis.直肠活检辅助溃疡性结肠炎的癌症控制
Gut. 1967 Oct;8(5):423-34. doi: 10.1136/gut.8.5.423.
2
In-situ and invasive carcinoma of the colon in patients with ulcerative colitis.溃疡性结肠炎患者的结肠原位癌和浸润癌。
Gut. 1972 Jul;13(7):566-70. doi: 10.1136/gut.13.7.566.
3
Demonstration of antigens related to colonic cancer in the human digestive system.人类消化系统中与结肠癌相关抗原的证明。
正常和病理结肠黏膜上皮细胞标志物的免疫组织化学。基于常规福尔马林和冷乙醇固定方法的结果比较。
Histochemistry. 1980;67(1):7-21. doi: 10.1007/BF00490083.
4
Immunoperoxidase study of the secretory immunoglobulin system in colonic neoplasia.结肠肿瘤中分泌性免疫球蛋白系统的免疫过氧化物酶研究。
J Clin Pathol. 1982 Jan;35(1):14-25. doi: 10.1136/jcp.35.1.14.
5
An immunoperoxidase study of epithelial marker antigens in ulcerative colitis with dysplasia and carcinoma.对伴有发育异常和癌的溃疡性结肠炎上皮标记抗原的免疫过氧化物酶研究。
J Clin Pathol. 1985 Jan;38(1):18-29. doi: 10.1136/jcp.38.1.18.
6
Heterogeneous epithelial expression of class II (HLA-DR) determinants and secretory component related to dysplasia in ulcerative colitis.与溃疡性结肠炎发育异常相关的II类（HLA - DR）决定簇及分泌成分的异质性上皮表达
Br J Cancer. 1987 Oct;56(4):419-24. doi: 10.1038/bjc.1987.217.
7
Value of sigmoidoscopy and biopsy in detection of carcinoma and premalignant change in ulcerative colitis.乙状结肠镜检查及活检在溃疡性结肠炎癌变及癌前病变检测中的价值
Gut. 1979 Jul;20(7):575-80. doi: 10.1136/gut.20.7.575.
8
Carcinoembryonic antigen (CEA) in the normal human small intestine: a light and electron microscopic study.正常人体小肠中的癌胚抗原（CEA）：光镜和电镜研究
Gut. 1977 Oct;18(10):786-91. doi: 10.1136/gut.18.10.786.
9
Localization of carcinoembryonic antigen in medullary thyroid carcinoma by immunofluorescent techniques.应用免疫荧光技术对甲状腺髓样癌中癌胚抗原进行定位。
Br J Cancer. 1977 Nov;36(5):572-6. doi: 10.1038/bjc.1977.233.
10
Immunohistochemistry of carcinoembryonic antigen: characterisation of cross-reactions with other glycoproteins.癌胚抗原的免疫组织化学：与其他糖蛋白交叉反应的特征
Gut. 1977 Oct;18(10):779-85. doi: 10.1136/gut.18.10.779.
Int J Cancer. 1970 Nov 15;6(3):352-60. doi: 10.1002/ijc.2910060305.
4
Evolution of cancer of the colon and rectum.结肠直肠癌的演变
Cancer. 1974 Sep;34(3):suppl:845-9. doi: 10.1002/1097-0142(197409)34:3+<845::aid-cncr2820340710>3.0.co;2-h.
5
"Precancer" lesions in ulcerative colits. A retrospective study of rectal biopsy and colectomy specimens.溃疡性结肠炎中的“癌前”病变。一项对直肠活检和结肠切除术标本的回顾性研究。
Cancer. 1974 Sep;34(3):suppl:835-44. doi: 10.1002/1097-0142(197409)34:3+<835::aid-cncr2820340709>3.0.co;2-t.
6
Rectal biopsy in inflammatory bowel disease.炎症性肠病中的直肠活检
N Engl J Med. 1972 Dec 28;287(26):1337-9. doi: 10.1056/NEJM197212282872607.
7
Peroxidase-labeled antibody. A new method of conjugation.过氧化物酶标记抗体。一种新的偶联方法。
J Histochem Cytochem. 1974 Dec;22(12):1084-91. doi: 10.1177/22.12.1084.
8
Immunological study of polyps of the colon.结肠息肉的免疫学研究
J Natl Cancer Inst. 1972 Jan;48(1):25-32.
9
Polyposis in ulcerative colitis.溃疡性结肠炎中的息肉病
Gut. 1975 Oct;16(10):792-5. doi: 10.1136/gut.16.10.792.
10
Association of an isomeric species of carcinoembryonic antigen with neoplasia of the gastrointestinal tract.癌胚抗原的一种异构体与胃肠道肿瘤的关联。
N Engl J Med. 1975 Jul 17;293(3):103-7. doi: 10.1056/NEJM197507172930301.