Davy T, Dick P T, Munk P
Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
Pediatr Infect Dis J. 1998 Jun;17(6):457-62. doi: 10.1097/00006454-199806000-00004.
Physicians are often called on to manage children with acute respiratory tract infections with cough when the clinical presentation may not allow a differentiation between viral and bacterial etiology. To develop guidelines for appropriate antibiotic use, it is necessary to understand the present prescribing patterns of physicians who manage children presenting with such an undifferentiated acute respiratory tract infection with cough (UARTIC).
To determine the variability of self-reported prescribing habits for antibiotics for children with UARTIC.
In this cross-sectional survey by a modified Dillman's Total Design Method, a mail-out questionnaire was administered to a random sample of 181 primary care family physicians and pediatricians (Toronto, Ontario, Canada) to assess perceptions of their own antibiotic-prescribing habit.
Completed questionnaires were received from 136 (75%) eligible physicians; 32% reported that > 10% of their office visits were for UARTIC. For a 3-day history of UARTIC 24% reported prescribing antibiotics or antibiotics in reserve (i.e. a prescription to be filled if the patient's condition does not improve) always or most times. This increased to 45% when UARTIC had worsened in the 24 h before the office visit (P < 0.001).
When a pediatric patient presented with UARTIC, antibiotics or antibiotics in reserve were prescribed in the absence of clear indicators of bacterial infection. Research- and evidence-based guidelines are needed to support rational antibiotic use for UARTIC.
当临床表现无法区分病毒和细菌病因时,医生经常需要诊治患有急性呼吸道感染并伴有咳嗽的儿童。为制定适当使用抗生素的指南,有必要了解诊治此类未分化的急性呼吸道感染并伴有咳嗽(UARTIC)儿童的医生目前的处方模式。
确定自我报告的针对UARTIC儿童使用抗生素的处方习惯的变异性。
在这项采用改良迪尔曼全面设计方法的横断面调查中,向181名基层医疗家庭医生和儿科医生(加拿大多伦多安大略省)的随机样本发放了邮寄问卷,以评估他们对自己抗生素处方习惯的看法。
136名(75%)符合条件的医生返回了完整问卷;32%的医生报告称,其门诊就诊中>10%是针对UARTIC。对于有3天UARTIC病史的患者,24%的医生报告总是或大多数时候会开具抗生素或备用抗生素(即如果患者病情没有改善则开具的处方)。当在门诊就诊前24小时UARTIC病情恶化时,这一比例增至45%(P<0.001)。
当儿科患者出现UARTIC时,在没有明确细菌感染指标的情况下就会开具抗生素或备用抗生素。需要基于研究和证据的指南来支持对UARTIC合理使用抗生素。