Nawa Y, Maruyama H, Ogata K
Department of Parasitology, Miyazaki Medical College, Japan.
Southeast Asian J Trop Med Public Health. 1997;28 Suppl 1:11-3.
Gnathostomiasis is an important food-borne parasitic zoonosis caused mainly by ingesting uncooked or undercooked flesh of freshwater fishes. Although four distinct species of the genus Gnathostoma were identified as the causative agents for human gnathostomiasis, human infections with G. doloresi have been found only in Japan, concentrated in Miyazaki Prefecture. So far we have found 25 cases in Miyazaki Prefecture. Although most of these patients were of cutaneous gnathostomiasis, two patients presented to the hospital with unusual clinical manifestations; one case was a pulmonary gnathostomiasis diagnosed by immunoserological methods, and the other was an ileus caused by migration of the late 3rd stage larva in the colonic tissue, which was found by post-operative histopathological examination. Although cutaneous lesions such as creeping eruption or mobile erythema are the common clinical features of gnathostomiasis, caution should be paid to the presence of such unusual cases.
颚口线虫病是一种重要的食源性寄生人畜共患病，主要因食用未煮熟或煮得不够熟的淡水鱼的鱼肉而感染。虽然已确定颚口线虫属的四个不同物种是人类颚口线虫病的病原体，但仅在日本宫崎县发现了多氏颚口线虫感染人类的病例，且病例集中于此。到目前为止，我们在宫崎县已发现25例病例。虽然这些患者大多为皮肤颚口线虫病，但有两名患者出现了不寻常的临床表现；一例是通过免疫血清学方法诊断出的肺颚口线虫病，另一例是术后组织病理学检查发现的结肠组织中第三期幼虫移行导致的肠梗阻。虽然匐行疹或游走性红斑等皮肤病变是颚口线虫病的常见临床特征，但对于此类不寻常病例的存在仍应予以关注。
