Addington J, el-Guebaly N, Campbell W, Hodgins D C, Addington D
Department of Psychiatry, University of Calgary, Alta., Canada.
Am J Psychiatry. 1998 Jul;155(7):974-6. doi: 10.1176/ajp.155.7.974.
This study was an uncontrolled trial to assess the efficacy of a smoking cessation group program modified for individuals with schizophrenia.
Fifty outpatients with schizophrenia were divided into five groups who met separately for seven weekly sessions of a smoking cessation program. The subjects' schizophrenic and extrapyramidal symptoms were assessed before the group sessions began and after they had been completed. Assessments of smoking were made at those times and at 3-month and 6-month follow-ups.
Forty-two percent of the subjects had stopped smoking at the end of the group sessions; 16% remained abstinent at 3 months, and 12% at 6 months. These changes were statistically significant. There was no change in the positive or negative symptoms of schizophrenia.
The results suggest that it is possible for individuals with schizophrenia to stop smoking.
本研究是一项非对照试验，旨在评估为精神分裂症患者量身定制的戒烟小组项目的疗效。
五十名精神分裂症门诊患者被分成五组，分别参加为期七周的戒烟项目课程。在小组课程开始前和结束后，对受试者的精神分裂症症状和锥体外系症状进行评估。在这些时间点以及3个月和6个月随访时对吸烟情况进行评估。
42%的受试者在小组课程结束时戒烟；3个月时16%的人仍保持戒烟状态，6个月时为12%。这些变化具有统计学意义。精神分裂症的阳性或阴性症状没有变化。
结果表明精神分裂症患者有可能戒烟。
