Vollmer W M, Svetkey L P, Appel L J, Obarzanek E, Reams P, Kennedy B, Aicher K, Charleston J, Conlin P R, Evans M, Harsha D, Hertert S
Kaiser Permanente Center For Health Research.
Ethn Dis. 1998;8(2):198-208.
The Dietary Approaches to Stop Hypertension (DASH) study was a National Heart, Lung, and Blood Institute multicenter trial that compared the impact of three dietary patterns on blood pressure (BP) among adults with high normal blood pressure or mild (Stage I) hypertension. DASH's high minority representation (two-thirds of the 459 randomized participants came from minority populations, and 60% of the cohort were African American) offered a valuable opportunity to assess factors affecting minority enrollment and retention in clinical trials of lifestyle modification. Recruitment strategies included targeted mailings to specific groups, mass mailings, community and worksite screenings, and mass media advertising; the four DASH clinical centers also reimbursed participants from $150 to $160. The most productive recruitment strategies tended to be mass mailings directed at a broad audience that was weighted toward, but not limited to, minority participants. DASH's African-American participants overwhelmingly (89%) cited health and dietary factors, such as learning more about blood pressure and healthy eating habits, as their primary reason for participating, while only six percent listed the financial incentives as their primary reason for participating. Eighty-eight percent of African-American respondents reported they would participate again in a similar study. The insights from DASH should help inform future efforts to recruit minority participants.
高血压防治饮食法(DASH)研究是美国国立心肺血液研究所开展的一项多中心试验,比较了三种饮食模式对血压正常高值或轻度(I期)高血压成年人血压的影响。DASH研究中有很高比例的少数族裔参与者(459名随机参与者中有三分之二来自少数族裔群体,且60%的队列参与者为非裔美国人),这为评估影响少数族裔参与和留在生活方式改变临床试验的因素提供了宝贵机会。招募策略包括针对特定群体的定向邮件、群发邮件、社区和工作场所筛查以及大众媒体广告;四个DASH临床中心还向参与者报销150至160美元。最有效的招募策略往往是针对广大受众的群发邮件,这些受众以少数族裔参与者为主,但不限于少数族裔。DASH研究中的非裔美国参与者绝大多数(89%)表示,了解更多血压知识和健康饮食习惯等健康和饮食因素是他们参与的主要原因,而只有6%的人将经济激励作为参与的主要原因。88%的非裔美国受访者表示他们会再次参与类似研究。DASH研究的见解应有助于为未来招募少数族裔参与者的工作提供参考。