婴儿猝死综合征中的子宫内脑损伤。

In utero brain lesions in SIDS.

作者信息

Obonai T, Takashima S

机构信息

Department of Mental Retardation and Birth Defect Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan.

出版信息

Pediatr Neurol. 1998 Jul;19(1):23-5. doi: 10.1016/s0887-8994(98)00008-3.

DOI:10.1016/s0887-8994(98)00008-3

PMID:9682880

Abstract

Serial examination of the cerebral hemispheres of 20 sudden infant death syndrome victims revealed high incidence of leukomalacia (40%), leptomeningeal glioneuronal heterotopias (70%) at the base of the cerebrum, and astrogliosis (65%) in the white matter and medulla reticular formation compared with 20 age-matched controls. These results suggest that an antepartum insult may become an important predisposing risk factor in some patients for sudden infant death syndrome.

摘要

对20名婴儿猝死综合征受害者的大脑半球进行的系列检查显示，与20名年龄匹配的对照组相比，白质软化症（40%）、大脑底部软脑膜神经胶质神经元异位（70%）以及白质和延髓网状结构中的星形胶质细胞增生（65%）的发生率较高。这些结果表明，产前损伤可能成为一些婴儿猝死综合征患者的重要诱发危险因素。