在感染幽门螺杆菌的胃癌患者中，胃体胃炎的严重表现具有特征性。
Severe expression of corpus gastritis is characteristic in gastric cancer patients infected with Helicobacter pylori.
作者信息
Miehlke S, Hackelsberger A, Meining A, Hatz R, Lehn N, Malfertheiner P, Stolte M, Bayerdörffer E
机构信息
Medical Department I, Technical University Hospital, Dresden, Germany.
出版信息
Br J Cancer. 1998 Jul;78(2):263-6. doi: 10.1038/bjc.1998.475.
Abstract
In 50 Helicobacter pylori-infected gastric carcinoma patients the corpus gastritis was significantly higher than in matched H. pylori-positive control subjects (P < 0.01). Atrophy and intestinal metaplasia (IM) occurred significantly more often in the antrum of carcinoma patients (P < 0.01). The odds ratio for gastric carcinoma was 8.85 for high-grade corpus gastritis and 8.04 when atrophy in the antrum was present.
摘要
在50例幽门螺杆菌感染的胃癌患者中，胃体胃炎的发生率显著高于匹配的幽门螺杆菌阳性对照受试者（P < 0.01）。萎缩和肠化生（IM）在癌患者的胃窦中发生的频率明显更高（P < 0.01）。高级别胃体胃炎患者患胃癌的优势比为8.85，胃窦存在萎缩时为8.04。
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本文引用的文献
1
THE TWO HISTOLOGICAL MAIN TYPES OF GASTRIC CARCINOMA: DIFFUSE AND SO-CALLED INTESTINAL-TYPE CARCINOMA. AN ATTEMPT AT A HISTO-CLINICAL CLASSIFICATION.胃癌的两种主要组织学类型：弥漫型和所谓的肠型癌。组织学临床分类的尝试。
Acta Pathol Microbiol Scand. 1965;64:31-49. doi: 10.1111/apm.1965.64.1.31.
2
Carcinoma arising from areas of intestinal metaplasia in the gastric mucosa.起源于胃黏膜肠化生区域的癌。
Br J Cancer. 1955 Sep;9(3):377-85. doi: 10.1038/bjc.1955.36.
3
Gastric carcinoma risk index in patients infected with Helicobacter pylori.
Virchows Arch. 1998 Apr;432(4):311-4. doi: 10.1007/s004280050171.
4
Differing degree and distribution of gastritis in Helicobacter pylori-associated diseases.幽门螺杆菌相关疾病中胃炎的不同程度及分布情况。
Virchows Arch. 1997 Jul;431(1):11-5. doi: 10.1007/s004280050063.
5
The risk of stomach cancer in patients with gastric or duodenal ulcer disease.胃溃疡或十二指肠溃疡病患者患胃癌的风险。
N Engl J Med. 1996 Jul 25;335(4):242-9. doi: 10.1056/NEJM199607253350404.
6
Helicobacter pylori and gastric cancer.幽门螺杆菌与胃癌
J Gastroenterol Hepatol. 1993 May-Jun;8(3):294-303. doi: 10.1111/j.1440-1746.1993.tb01202.x.
7
Helicobacter pylori and intestinal metaplasia: comparison between British and Yemeni patients.
Am J Gastroenterol. 1993 Sep;88(9):1373-6.
8
Helicobacter pylori and nucleolar organizer regions in the gastric antral mucosa.
Am J Clin Pathol. 1994 May;101(5):656-60. doi: 10.1093/ajcp/101.5.656.
9
Gastric cancer--a long-term consequence of Helicobacter pylori infection?胃癌——幽门螺杆菌感染的长期后果？
Scand J Gastroenterol Suppl. 1994;201:24-7.
10
Relationship between infective load of Helicobacter pylori and reactive oxygen metabolite production in antral mucosa.幽门螺杆菌感染负荷与胃窦黏膜活性氧代谢产物产生之间的关系。
Scand J Gastroenterol. 1994 May;29(5):419-24. doi: 10.3109/00365529409096832.
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