Cahill L, McGaugh J L
Center for the Neurobiology of Learning and Memory and Dept of Psychobiology, University of California Irvine, 92697-3800, USA.
Trends Neurosci. 1998 Jul;21(7):294-9. doi: 10.1016/s0166-2236(97)01214-9.
Neuroscience is witnessing growing interest in understanding brain mechanisms of memory formation for emotionally arousing events, a development closely related to renewed interest in the concept of memory consolidation. Extensive research in animals implicates stress hormones and the amygdaloid complex as key, interacting modulators of memory consolidation for emotional events. Considerable evidence suggests that the amygdala is not a site of long-term explicit or declarative memory storage, but serves to influence memory-storage processes in other brain regions, such as the hippocampus, striatum and neocortex. Human-subject studies confirm the prediction of animal work that the amygdala is involved with the formation of enhanced declarative memory for emotionally arousing events.
神经科学领域对于理解情绪唤起事件的记忆形成的大脑机制的兴趣日益浓厚，这一发展与对记忆巩固概念的重新关注密切相关。对动物的广泛研究表明，应激激素和杏仁核复合体是情绪事件记忆巩固的关键相互作用调节因子。大量证据表明，杏仁核不是长期显性或陈述性记忆存储的部位，而是起到影响其他脑区（如海马体、纹状体和新皮层）记忆存储过程的作用。人体研究证实了动物研究的预测，即杏仁核参与了对情绪唤起事件增强的陈述性记忆的形成。
