Squire L R
Science. 1986 Jun 27;232(4758):1612-9. doi: 10.1126/science.3086978.
Recent studies of animals with complex nervous systems, including humans and other primates, have improved our understanding of how the brain accomplishes learning and memory. Major themes of recent work include the locus of memory storage, the taxonomy of memory, the distinction between declarative and procedural knowledge, and the question of how memory changes with time, that is, the concepts of forgetting and consolidation. An important recent advance is the development of an animal model of human amnesia in the monkey. The animal model, together with newly available neuropathological information from a well-studied human patient, has permitted the identification of brain structures and connections involved in memory functions.
最近对包括人类和其他灵长类动物在内的具有复杂神经系统的动物的研究，增进了我们对大脑如何完成学习和记忆的理解。近期研究的主要主题包括记忆存储的位置、记忆的分类、陈述性知识和程序性知识之间的区别，以及记忆如何随时间变化的问题，即遗忘和巩固的概念。最近一项重要进展是在猴子身上开发出了人类失忆症的动物模型。该动物模型，连同从一位经过充分研究的人类患者那里新获得的神经病理学信息，使得确定参与记忆功能的脑结构和连接成为可能。
