Takenaka S, Murakami S, Shinke R, Aoki K
Division of Science of Biological Resources, Graduate School of Science and Technology, Kobe University, Rokko, Kobe 657-8501, Japan.
Arch Microbiol. 1998 Aug;170(2):132-7. doi: 10.1007/s002030050624.
A novel pathway for 2-aminophenol metabolism by Pseudomonas sp. AP-3 is proposed. The proposed pathway is similar to that known for meta-cleavage of catechol except that one of the hydroxyl groups on the metabolites is replaced by an amino group. During the degradation of 2-aminophenol, 2-amino-2,4-pentadienoic acid is the last metabolite containing an amino group. We, therefore, propose a modified meta-cleavage pathway for the 2-aminophenol metabolism.
提出了一种由假单胞菌属AP-3代谢2-氨基酚的新途径。所提出的途径与已知的儿茶酚间位裂解途径相似,只是代谢产物上的一个羟基被氨基取代。在2-氨基酚的降解过程中,2-氨基-2,4-戊二烯酸是最后一个含氨基的代谢产物。因此,我们提出了一种用于2-氨基酚代谢的改良间位裂解途径。