Duhamel G E, Klein E C, Elder R O, Gebhart C J
Department of Veterinary and Biomedical Sciences, University of Nebraska, Lincoln 68583-0905, USA.
Vet Pathol. 1998 Jul;35(4):300-3. doi: 10.1177/030098589803500410.
Light microscopic and ultrastructural changes of naturally acquired proliferative enteropathy were observed in two of three young sentinel New Zealand White rabbits. The etiologic agent, Lawsonia intracellularis, was demonstrated in the tissues using morphologic, immunohistochemical, and molecular methods. Proliferative enteropathy was associated with infection of villous and crypt enterocytes by intracellular organisms genotypically and antigenically related to L. intracellularis of various other animal species.
在三只作为哨兵的幼年新西兰白兔中，有两只观察到了自然获得性增生性肠炎的光镜和超微结构变化。使用形态学、免疫组织化学和分子方法在组织中证实了病原体——胞内劳森菌。增生性肠炎与绒毛和隐窝肠上皮细胞被与其他各种动物物种的胞内劳森菌在基因型和抗原性上相关的胞内生物体感染有关。
