翼状胬肉和平行斑的患病率:蓝山眼研究
Prevalence of pterygium and pinguecula: the Blue Mountains Eye Study.
作者信息
Panchapakesan J, Hourihan F, Mitchell P
机构信息
University of Sydney Department of Ophthalmology, New South Wales, Australia.
出版信息
Aust N Z J Ophthalmol. 1998 May;26 Suppl 1:S2-5. doi: 10.1111/j.1442-9071.1998.tb01362.x.
PURPOSE
The present study aimed to describe the prevalence of pterygium and pinguecula in an older population and to examine associations with skin, hair and eye colour, skin sun sensitivity, sun-related skin damage and skin cancer
METHODS
The Blue Mountains Eye Study examined 3564 people aged 49 years or older Slit-lamp examination recorded pterygium and pinguecula and a questionnaire was used to collect information on physical variables.
RESULTS
Two hundred and sixty-six subjects (7.3%) had pterygium (or had a history of pterygium surgery) and 2521 (69.5%) had pinguecula present in either eye. Significantly more men (11%) than women (4.5%) had pterygium (odds ratio (OR) 2.63; 95% confidence interval (CI) 2.03-3.42). This sex difference was aso found for pinguecula, present in 73.6 and 66.3% of men and women, respectively (OR 1.5; 95% CI 1.3-1.7). A s ight age-related increase in prevalence was found for both pterygium and pinguecula.
CONCLUSIONS
The study found significant associations between pterygium and increased pigmentation (skin and hair colour), decreased skin sun sensitivity and sun-related skin damage. The age- and sex-specific pterygium prevalence rates in the present study are simi ar to rates found in non-Aboriginals examined in the 1980 Australian Trachoma Programme.
目的
本研究旨在描述老年人群中翼状胬肉和睑裂斑的患病率,并研究其与皮肤、头发和眼睛颜色、皮肤对阳光的敏感性、与阳光相关的皮肤损伤以及皮肤癌之间的关联。
方法
蓝山眼研究对3564名49岁及以上的人进行了检查。裂隙灯检查记录了翼状胬肉和睑裂斑情况,并使用问卷收集身体变量信息。
结果
266名受试者(7.3%)患有翼状胬肉(或有翼状胬肉手术史),2521名(69.5%)受试者一眼或双眼有睑裂斑。患有翼状胬肉的男性(11%)明显多于女性(4.5%)(优势比(OR)2.63;95%置信区间(CI)2.03 - 3.42)。睑裂斑在男性和女性中的患病率也存在这种性别差异,分别为73.6%和66.3%(OR 1.5;95% CI 1.3 - 1.7)。翼状胬肉和睑裂斑的患病率均随年龄略有增加。
结论
该研究发现翼状胬肉与色素沉着增加(皮肤和头发颜色)、皮肤对阳光敏感性降低以及与阳光相关的皮肤损伤之间存在显著关联。本研究中按年龄和性别划分的翼状胬肉患病率与1980年澳大利亚沙眼项目中对非原住民检查发现的患病率相似。