Korhonen J, Alfthan H, Stenman U H, Ylöstalo P
Department of Obstetrics and Gynecology, Helsinki University, Central Hospital, Finland.
Fertil Steril. 1996 May;65(5):922-4. doi: 10.1016/s0015-0282(16)58261-2.
To investigate serum creatine kinase (CK) levels in pregnant women with ectopic pregnancy (EP), spontaneous abortion, and normal pregnancy with comparable serum hCG concentrations.
A retrospective, case-controlled study.
Helsinki University Central Hospital, Helsinki, Finland.
Forty-four patients with a suspicion of EP of which 15 had laparoscopically confirmed tubal pregnancies; 15 had a spontaneous abortion, a blighted ovum, or a missed abortion; and 14 patients a normal intrauterine pregnancy.
The diagnosis was made by transvaginal sonography and serum hCG determinations either at admission or after repeated examinations. Ectopic pregnancy was confirmed and treated by laparoscopy.
Serum CK and hCG levels.
No significant differences in CK levels were observed between the groups by one-way analysis of variance and no correlation was found between serum CK and hCG levels within any group.
Creatine kinase does not appear to be useful in the diagnosis of early EP.
在血清人绒毛膜促性腺激素（hCG）浓度相当的情况下，研究异位妊娠（EP）、自然流产孕妇及正常妊娠孕妇的血清肌酸激酶（CK）水平。
一项回顾性病例对照研究。
芬兰赫尔辛基大学中心医院。
44例疑似EP患者，其中15例经腹腔镜确诊为输卵管妊娠；15例发生自然流产、胚胎停育或稽留流产；14例为正常宫内妊娠。
入院时或经反复检查后，通过经阴道超声检查及血清hCG测定进行诊断。通过腹腔镜确诊并治疗异位妊娠。
血清CK和hCG水平。
通过单因素方差分析，各组间CK水平无显著差异，且任何一组内血清CK与hCG水平均无相关性。
肌酸激酶似乎对早期EP的诊断无帮助。
