酮替芬与色甘酸二钠在支气管激发试验中的比较。
Comparison between ketotifen and DSCG in bronchial challenge.
作者信息
Pauwels R, Lamont H, Van Der Straeten M
出版信息
Clin Allergy. 1978 May;8(3):289-93. doi: 10.1111/j.1365-2222.1978.tb03226.x.
Abstract
A double-blind cross-over study showed that orally taken ketotifen and inhaled DSCG have a comparable protective effect on allergen-induced bronchoconstriction. Both drugs significantly inhibit the immediate bronchial reaction after a 3 day treatment with either 1 mg ketotifen or 20 mg DSCG four times daily. Late reactions, which occurred in three out of the ten patients, were inhibited in two of the three patients by ketotifen as by DSCG.
摘要
一项双盲交叉研究表明，口服酮替芬和吸入色甘酸二钠对变应原诱发的支气管收缩具有相似的保护作用。每日4次给予1毫克酮替芬或20毫克色甘酸二钠，治疗3天后，两种药物均能显著抑制即刻支气管反应。10名患者中有3名出现迟发反应，其中2名患者的迟发反应被酮替芬和色甘酸二钠同样抑制。
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