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痰标本中鸟分枝杆菌复合群与结核分枝杆菌共存对药敏试验结果的影响:病例报告及实验探讨

Modification of results of drug susceptibility tests by coexistence of Mycobacterium avium complex with Mycobacterium tuberculosis in a sputum sample: case report and experimental considerations.

作者信息

Suzuki K, Kimoto T, Tsuyuguchi K, Matsumoto H, Niimi A, Tanaka E, Murayama T, Amitani R

机构信息

Department of Infection and Inflammation, Chest Disease Research Institute, Kyoto University, Sakyo-ku, Kyoto, 606 Japan.

出版信息

J Clin Microbiol. 1998 Sep;36(9):2745-7. doi: 10.1128/JCM.36.9.2745-2747.1998.

Abstract

We report on a patient whose sputum contained both Mycobacterium tuberculosis and Mycobacterium avium complex (MAC). The MAC failed to be detected by the PCR-based AMPLICOR test. The unrecognized coexistence of MAC in the sample modified the results of drug susceptibility tests. Experiments revealed that the presence of both M. tuberculosis and MAC was not detected by the AMPLICOR test under certain conditions.

摘要

我们报告了一名患者,其痰液中同时含有结核分枝杆菌和鸟分枝杆菌复合群(MAC)。基于PCR的AMPLICOR检测未能检测到MAC。样本中未被识别的MAC共存改变了药敏试验结果。实验表明,在某些条件下,AMPLICOR检测未检测到结核分枝杆菌和MAC同时存在的情况。

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本文引用的文献

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Resistance to antituberculosis drugs in Japan.日本对抗结核药物的耐药性。
Tuber Lung Dis. 1996 Apr;77(2):130-5. doi: 10.1016/s0962-8479(96)90027-1.

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