Seow L T, Chiu H H, Tye C Y
Anaesth Intensive Care. 1976 Aug;4(3):239-44. doi: 10.1177/0310057X7600400312.
A randomized double-blind trial compared 1-0% etidocaine and 1-5% lignocaine (both with 1/200,000 adrenaline), for caudal anaesthesia for pelvic floor repair. Etidocaine was highly effective for the surgical procedure, with rapid onset of action, adequate muscle relaxation and longer duration of action. Its use for post-operative analgesia may be hindered by the concomitant immobilization of the legs. The problem of tachyphylaxis with etidocaine needs further investigation.
一项随机双盲试验比较了1.0%依替卡因和1.5%利多卡因(均含1/200,000肾上腺素)用于盆底修复骶管麻醉的效果。依替卡因对手术过程高效,起效迅速,肌肉松弛充分且作用持续时间长。其用于术后镇痛可能会因腿部同时出现的麻痹而受到阻碍。依替卡因快速耐受性的问题需要进一步研究。