Russo F, Di Pasquale B, Romano G, Vicentini C, Manieri C, Tubaro A, Miano L
Dipartimento di Discipline Chirurgiche, Università degli Studi, L'Aquila.
Arch Ital Urol Androl. 1998 Jun;70(3 Suppl):15-24.
The AUA 7 score was originally designed and validated to be self administrated to patients with LUTS, its subsequent endorsement by the WHO - BPH committee made it the most widely used. Translation into different was provided and sometime validated. Aim of the study was to investigate the possibility to self administer the IPSS questionnaire to patients referred to our Institution for lower urinary tract symptoms. Two hundred and thirty-tree consecutive patients were given the IPSS questionnaire as a part of the routine diagnostic schedule; a senior resident was available to answer any possible question from the patient. After the form was returned, a second IPSS questionnaire was filled in by investigator following patient interview. Data were entered into an Excel database and the following parameters were investigate: number of forms completely filled in by patient, number of question answered in incomplete forms, degree of concordance between patient and investigator. One hundred and fifteen patients were able to fill the AUA 7 form completely; the quality of life question was answered by ninety-six patients only. Comparison of individual scores provided by the patient or assigned by the investigator showed a trend for the physician to underscore the patient problem for question 1-4 and to overestimate it in questions 5 to 7. At the lower range of the IPS score (0-7) no significant different between physician and patient was found. In the intermediate range (8-19) the physician tended to overestimate the patient symptoms. The reverse situations was found in the high score range (20-35). Globally, there was a trend for the patient score to be higher than the one assigned by the investigator, Doctor IPSS and quality of life scores appeared to be significantly related. No relation was found between doctor IPSS and the degree of bladder outlet obstruction as measured by parameter of pressure-flow study and diagnostic nomograms. The IPSS form appeared to be a difficult questionnaire for our patients and less than half of them were able to fill it in properly. Overall, the investigators tended to underestimate the patient voiding disturbances. Careful linguistic review of the Italian version of the IPSS questionnaire is required to make self evaluation of patient symptom possible. Symptom grading by a trained investigator did not seem to introduce any significant bias which might be of importance for the sake of clinical trials.
AUA 7评分最初是为下尿路症状(LUTS)患者自行管理而设计和验证的,随后被世界卫生组织良性前列腺增生委员会认可,成为使用最广泛的评分。该评分已被翻译成不同语言并在某些情况下得到验证。本研究的目的是调查向下尿路症状患者自行发放国际前列腺症状评分(IPSS)问卷的可行性。233例连续患者在常规诊断流程中被给予IPSS问卷;一名高级住院医师随时准备回答患者的任何问题。问卷返回后,研究者在与患者面谈后填写第二份IPSS问卷。数据录入Excel数据库,并对以下参数进行研究:患者完全填写的问卷数量、未完整填写问卷中回答的问题数量、患者与研究者之间的一致性程度。115例患者能够完全填写AUA 7表格;只有96例患者回答了生活质量问题。比较患者自行填写或研究者给出的个体评分发现,医生在问题1-4上有低估患者问题的趋势,而在问题5至7上有高估的趋势。在IPSS评分的较低范围(0-7),医生和患者之间未发现显著差异。在中间范围(8-19),医生倾向于高估患者症状。在高分范围(20-35)发现了相反的情况。总体而言,患者评分有高于研究者给出评分的趋势,医生IPSS评分和生活质量评分似乎显著相关。在通过压力-流率研究参数和诊断列线图测量的膀胱出口梗阻程度与医生IPSS评分之间未发现相关性。IPSS表格对我们的患者来说似乎是一份困难的问卷,不到一半的患者能够正确填写。总体而言,研究者倾向于低估患者的排尿障碍。需要对IPSS问卷的意大利语版本进行仔细的语言审查,以使患者能够自行评估症状。由训练有素的研究者进行症状分级似乎不会引入任何可能对临床试验很重要的显著偏差。