一种“单问题夜尿症评分”在评估良性前列腺增生症下尿路症状方面与“国际前列腺症状评分”的准确性比较：在赞比亚恩多拉教学医院进行的一项研究。

Accuracy of a "Single Question Nocturia Score" compared to the "International Prostate Symptoms Score" in the evaluation of lower urinary tract symptoms in benign prostatic hyperplasia: A study performed at Ndola Teaching Hospital, Ndola, Zambia.

机构信息

Medical Student, Copperbelt University School of Medicine, Ndola, Zambia.

Professor of Urology, Copperbelt University School of Medicine, Ndola, Zambia.

出版信息

PLoS One. 2018 Jun 26;13(6):e0198096. doi: 10.1371/journal.pone.0198096. eCollection 2018.

DOI:10.1371/journal.pone.0198096

PMID:29944653

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6019394/

Abstract

INTRODUCTION

The International Prostate Symptom Score (IPSS) is a useful tool approved by the World Health Organisation and the American Urological Association to measure the severity of lower urinary tract symptoms (LUTS). Although commonly used in urological practice, the IPSS has faced many challenges in terms of its usage in developing countries. In our setting, most patients presenting with this condition are elderly patients with a low literacy level. Given this background, the IPSS could be time consuming and difficult to administer to such patients and it may lead to additional costs to the services.

OBJECTIVES

The objective of this study was to compare the accuracy of a Single Question Nocturia Score (SQNS) with the IPSS in evaluation of lower urinary tracts symptoms in men with Benign prostatic hyperplasia(BPH).

METHODS

The study was designed as a cross-sectional study using researcher-administered IPSS and SQNS questionnaires. The sensitivity, specificity, and correlation coefficient were used to compare the results obtained. Sensitivity was defined as the ability of the SQNS to detect severe-to-moderate symptoms, whereas specificity was defined as the ability of the SQNS to detect mild-to-no symptoms.

RESULTS

We recruited 162 patients with an age range between 50 and 88 years. The mean age was 66.7 (standard deviation ± 8.97 years). The IPSS showed that 85 patients (52%) presented with mild symptoms, and 77 patients (48%) presented with severe-to-moderate symptoms. In contrast, the SQNS showed that 88 patients (54.3%) presented with mild symptoms and 74 patients (46.7%) presented with severe-to-moderate symptoms. The sensitivity of the SQNS was 91%, and the specificity was 87%. The correlation coefficient of the SQNS to IPSS using Pearson correlation coefficient, was 0.74. This study showed that in our setting, the SQNS may be used as an alternative to the IPSS in assessing the severity of LUTS in men with BPH especially in a busy clinic.

摘要

简介

国际前列腺症状评分（IPSS）是世界卫生组织和美国泌尿外科学会批准的一种有用的工具，用于衡量下尿路症状（LUTS）的严重程度。尽管在泌尿科实践中广泛使用，但 IPSS 在发展中国家的使用方面面临许多挑战。在我们的环境中，大多数出现这种情况的患者都是文化程度较低的老年患者。鉴于这种背景，IPSS 可能会耗费大量时间，并且难以管理给这些患者，并且可能会给服务带来额外的成本。

目的

本研究的目的是比较单问题夜尿症评分（SQNS）与 IPSS 在评估良性前列腺增生（BPH）男性下尿路症状中的准确性。

方法

该研究采用研究者管理的 IPSS 和 SQNS 问卷进行横断面研究。使用敏感性、特异性和相关系数来比较获得的结果。敏感性定义为 SQNS 检测到严重至中度症状的能力，而特异性定义为 SQNS 检测到轻度至无症状的能力。

结果

我们招募了年龄在 50 岁至 88 岁之间的 162 名患者。平均年龄为 66.7（标准差±8.97 岁）。IPSS 显示 85 名患者（52%）表现为轻度症状，77 名患者（48%）表现为严重至中度症状。相比之下，SQNS 显示 88 名患者（54.3%）表现为轻度症状，74 名患者（46.7%）表现为严重至中度症状。SQNS 的敏感性为 91%，特异性为 87%。使用 Pearson 相关系数的 SQNS 与 IPSS 的相关系数为 0.74。本研究表明，在我们的环境中，SQNS 可替代 IPSS 用于评估 BPH 男性的 LUTS 严重程度，尤其是在繁忙的诊所。